26 September 2020>: Articles
SARS-CoV-2 Infection and COVID-19 in 5 Patients in Ecuador After Prior Treatment with Hydroxychloroquine for Systemic Lupus Erythematosus
Unusual clinical course, Diagnostic / therapeutic accidents, Unusual setting of medical care, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
María Fernanda Zurita B , Adriana Iglesias Arreaga B* , Adriana A Luzuriaga Chavez F , Luis Zurita ADOI: 10.12659/AJCR.927304
Am J Case Rep 2020; 21:e927304
Table 2. Clinical characteristics and laboratory values for lupus patients with COVID-19.
Characteristics | n=5 (%) |
---|---|
Fever | 3 (60) |
Chills | 1 (20) |
Dry cough | 2 (40) |
Chest pain | 3 (60) |
Dyspnea | 2 (40) |
Hypogeusia | 2 (40) |
Anosmia | 2 (40) |
Odynophagia | 2 (40) |
Asthenia | 3 (60) |
Myalgias | 2 (40) |
Diarrhea | 1 (20) |
Headache | 1 (20) |
Polymerase chain reaction (PCR) | 5 (100) |
Positive PCR on admission | 0 (0) |
Negative PCR on admission | 0 (0) |
Positive PCR at discharge | 5 (100) |
Negative PCR at discharge | 5 (100) |
Immunoassay: COVID-19 IgG/IgM Rapid test | |
Leukopenia ( | 2 (40) |
Lymphopenia ( | 5 (100) |
Thrombocytopenia ( | 1 (20) |
Lactate dehydrogenase (LDH) | |
LDH: Within normal range ( | 5 (100) |
LDH: Moderately increased (250–500 U/l) | 0 (0) |
LDH: Highly increased (>500 U/l) | 0 (0) |
Ferritin | |
Normal value (10–150 ng/ml) | 5 (100) |
Above the upper limit | 0 (100) |
Procalcitonin | |
Normal value ( | 5 (100) |
Abnormal value (>0.5 ng/ml) | 0 (0) |
Interleukin 6 | |
Normal value ( | 3 (60) |
Abnormal value (>6.00 pg/mL) | 2 (40) |
Positive D-dimer (>250 ng/mL) | 1 (20) |
Normal | 4 (80) |
Abnormal | 0 (0) |
Normal | 4 (80) |
Abnormal | 1 (20) |
Chest CT findings – chest computed tomography findings. * Patient had a ground-glass opacity (GGO) on the CT. |