17 December 2020
: Case report 
Sedation After a Trial of Mixed Amphetamine Salts in a Boy with Attention-Deficit/Hyperactivity Disorder
Unusual or unexpected effect of treatment, Unexpected drug reaction
Raed Al Awami1EF, Ammar Albanna23AEF*DOI: 10.12659/AJCR.928269
Am J Case Rep 2020; 21:e928269
Table 1. Assessment of causality of the adverse drug reaction using the Naranjo score.
| No. | Question | Yes | No | Do not know |
|---|---|---|---|---|
| 1 | Are there previous conclusion reports on this reaction? | +1 | 0 | |
| 2 | Did the adverse event appear after the suspect drug was administered? | −1 | 0 | |
| 3 | Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | 0 | 0 | |
| 4 | Did the adverse reaction reappear when the drug was re-administered? | −1 | 0 | |
| 5 | Are there alternative causes that could solely have caused the reaction? | −1 | 0 | |
| 6 | Did the reaction reappear when a placebo was given? | −1 | 0 | |
| 7 | Was the drug detected in the blood (or other fluids) in a concentration known to be toxic? | +1 | 0 | |
| 8 | Was the reaction more severe when the dose was increased, or less severe when the dose was decreased? | +1 | 0 | |
| 9 | Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | +1 | 0 | |
| 10 | Was the adverse event confirmed by objective evidence? | 0 | 0 | |
| Interpretation | ≥/5−8=Probable/1–4=Possible/≤0=Doubtful | |||