17 February 2021
: Case report
Idiopathic Acquired Hemophilia A, a Rare Cause of Bleeding: A Case Report and Literature Review
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Carlos Andrés Regino1ABCDEFG*, José C. Alvarez1ABCDEFG, Leonardo Mejía Buriticá2ABCDEFG, Natalí Uribe Pulido1ABCDEF, Valeria Torres Yepes3ABCDEFG, José D. Torres24ABCDEFGDOI: 10.12659/AJCR.929401
Am J Case Rep 2021; 22:e929401
Table 2. Laboratory findings of case 2.
Test | Result |
---|---|
Coagulation tests | PT: 11.9” control: 13.3”INR: 1.0PTT: 126” control: 26”FVIII: 1.58%, Factor IX 100% |
Mixing tests | Baseline PTT: 162”Correction with normal plasma: 69.7”Incubation of 2 hours at 37ºC: no coagula detected |
Bethesda Units | 9.7 |
Other diagnostic tests | RF: negativeANA: 1: 80 homogeneous patternENA: negativeComplement C3 and C4: normalHIV, HbsAg, HCV antibodies: negativeUpper endoscopy: no malignancy, hiatal herniaColonoscopy: normalContrast chest and abdomen tomography without malignancy |
PT – prothrombin time; PTT – partial thromboplastin time; RF – rheumatoid factor; ANA – antinuclear antibodies; ENA – extractable nuclear antigens. |