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14 June 2021: Articles

A Young Woman with Excessive Fat in Lower Extremities Develops Disordered Eating and Is Subsequently Diagnosed with Anorexia Nervosa, Lipedema, and Hypermobile Ehlers-Danlos Syndrome

Challenging differential diagnosis, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology

Thomas F. Wright B* , Karen L. Herbst D

DOI: 10.12659/AJCR.930840

Am J Case Rep 2021; 22:e930840

Table 2. Diagnostic criteria of lipedema: International consensus [8].

• Onset at puberty, pregnancy, and menopause-progressive with age
• Uncontrolled localized fat deposition involving the lower extremities (usually legs and thighs)
• Symmetric increase in adipose tissue (“two-body syndrome”)
• Tired “heavy” legs
• Pain to touch or pressure may be mild or severe
• Easy bruising
• Hands and feet usually not affected (unlike lymphedema)
• Cuffs or bulges develop around joints (eg, ankles, knees, elbows, and wrists)
• Negative Stemmer’s sign
• Palpable spheroids in lipedema fat
• Reduced ambulation, decreased social activity

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923