Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

04 June 2021: Articles

Xanthomatous Inflammatory Infiltrate Involving the Spleen: An Unusual Presentation of Erdheim-Chester Disease and Review of the Literature

Rare disease

Gioia Di Stefano ** , Massimo Granai * , Francesco Giudici B , Giuliana Roselli B , Stefano Lazzi A , Raffaella Santi A

DOI: 10.12659/AJCR.931060

Am J Case Rep 2021; 22:e931060

Table 2. Cases of ECD with spleen localization.

AuthorsSex, ageClinical presentationRadiologic investigationsMultisystemicHP*Skeletal involvement
Rao et al. (2005)M, 48Dry cough and pleuritic chest painCT: increased interstitial septal markings, bilateral ground glass infiltrates, and a small right pleural effusionYesPresent
Busemann et al. (2007)M, 49Abdominal distension, weight loss, night sweats and fever, and hepatosplenomegalyCT: large retroperitoneal massYesPresent+
Dickson et al. (2008)F, 77Progressive dyspnea and peripheral edema, after she presented with pericardial effusion and constrictive pericarditisCT: mediastinal and lung changes consistent with metastatic carcinoma and multiple suspicious liver lesionsYesNot described
Gaspar et al. (2017)F, 24During puerperium presented with fever, rash, and jaundiceCT: hepatosplenomegalyYesPresent
HP – hemophagocytosis.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923