06 June 2021: Articles
Ileal Neuroendocrine Tumor in a Patient with Sclerosing Mesenteritis: Which Came First?
Unusual clinical course, Challenging differential diagnosis, Patient complains / malpractice, Rare disease
Cristine Pathirannehalage Don A* , Daniele Sforza A , Leandro Siragusa A , Bruno Sensi A , Matteo Ciancio Manuelli D , Rossana Telesca B , Luca Savino B , Valentina Ferrazzoli B , Simona Grande B , Massimo Villa D , Michele Grande BDOI: 10.12659/AJCR.931372
Am J Case Rep 2021; 22:e931372
Table 1. TNM classification of JI-NETs according to ENETS/UICC and AJCC.
| T – Primary tumor | ||
|---|---|---|
| ENETS/UICC | AJCC | |
| Primary tumor cannot be assessed | Primary tumor cannot be assessed | |
| No evidence of primary tumor | No evidence of primary tumor | |
| Tumor invades mucosa or submucosa and size ≤1 cm | Tumor invades mucosa or submucosa and size ≤1 cm | |
| Tumor invades muscolaris propria or size >1 cm | Tumor invades muscolaris propria or size >1 cm | |
| Tumor invades subserosa without penetration of overlying serosa | Tumor invades subserosa without penetration of overlying serosa | |
| Tumor invades peritoneum/other organs | Tumor invades peritoneum/other organs | |
| TNM – tumor, node, metastasis; JI-NETs – jejunoileal neuroendocrine tumors; ENETS – European Neuroendocrine Tumor Society; UICC – International Union Against Cancer; AJCC, American Joint Committee on Cancer. | ||
| N – Regional lymph node metastasis | ||
| ENETS/UICC | AJCC | |
| Regional lymph nodes cannot be assessed | Regional lymph nodes cannot be assessed | |
| No regional lymph node metastasis | No regional lymph node metastasis | |
| Regional lymph node metastasis | Regional lymph node metastasis less than 12 nodes | |
| Large mesenteric masses (>2 cm) and/or extensive nodal deposits (12 or greater), especially those that encase the superior mesenteric vessels | ||
| TNM – tumor, node, metastasis; JI-NETs – jejunoileal neuroendocrine tumors; ENETS – European Neuroendocrine Tumor Society; UICC – International Union Against Cancer; AJCC, American Joint Committee on Cancer. | ||
| M – Distant metastasis | ||
| ENETS/UICC | AJCC | |
| Distant metastasis cannot be assessed | Distant metastasis cannot be assessed | |
| No distant metastasis | No distant metastasis | |
| Distant metastasis | Distant metastasis | |
| Metastasis to liver | ||
| Metastasis in at least 1 extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone) | ||
| Both hepatic and extrahepatic metastasis | ||
| TNM – tumor, node, metastasis; JI-NETs – jejunoileal neuroendocrine tumors; ENETS – European Neuroendocrine Tumor Society; UICC – International Union Against Cancer; AJCC, American Joint Committee on Cancer. | ||