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12 November 2021: Articles

Concurrent Breast Carcinoma and Follicular Lymphoma: A Case Series

Challenging differential diagnosis, Rare coexistence of disease or pathology

Tabinda Saleem E , Kaihong Mi E , Rajan Pathak F , Kolsoum Yari E , Kit Lu A*

DOI: 10.12659/AJCR.931772

Am J Case Rep 2021; 22:e931772

Table 2. Previously reported cases.

YearAuthorPatient descriptionPrimary breast carcinomaPrimary managementSecond primary malignancyFollow up management
2010Laudenschlager al []5 52-year-old femaleInvasive ductal carcinoma of the right breastMastectomy with sentinel LN biopsyLow-grade follicular lymphoma 1/22 LNAdjuvant chemo for breast CA with surveillance for FL
1998Niedermayr et al []6 87-year-old femaleInvasive lobular carcinoma of right breastLumpectomy f/b tamoxifen therapyStage IV diffuse large B cell lymphomaLumpectomy f/b CHOP combination chemo with complete remission
2008Al Hussaini et al []7 50-year-old femaleInvasive mucinous carcinoma of left breastMastectomy with sentinel LN dissectionStage II SLL/CLL in dissected LNChemotherapy with cyclophosphamide and prednisolone for CLL resulting in complete remission
2005Barranger et al []8 61-year-old femaleInvasive ductal carcinoma of left breastLumpectomy with axillary LN dissectionB cell follicular lymphoma in situ in non-sentinel LNEssentially treated for breast CA
2004Benoit et al []9 53-year-old femaleAdenocarcinoma of right breastSentinel LN biopsyCo-occurrence of metastatic breast CA and Waldenstrom-type low grade lymphoma in non-sentinel LN
2002Frei et al []10 63-year-old femaleInvasive ductal carcinoma of left breast and DLBCL of right breastBilateral lumpectomiesRadiotherapy and tamoxifen therapy for left breast and CHOP therapy for right breast
2014Nishikawa et al []11 82-year-old femaleInvasive lobular carcinoma of the left axillary accessory mammary glandMastectomy f/b tamoxifen therapyDiffuse large B cell lymphoma (DLBCL) of left breast.No chemo, 3-month surveillance, no metastasis of lymphoma but develop adenocarcinoma of rectum underwent Hartman’s procedure
2019Alakeel et al []12 65-year-old femaleDuctal carcinoma in Situ of left breastStereotactic biopsyIntravascular large B cell lymphoma in adjacent breast tissuePatient lost to follow up
DLBCL – diffuse large B cell lymphoma; SLL – small lymphocytic leukemia; CLL – chronic lymphocytic leukemia; LN – lymph node; FL – follicular lymphoma; CA – carcinoma; CHOP – cyclophosphamide, hydroxydaunorubicin, oncovin (vincristine), and prednisone.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923