Hemophagocytic Lymphohistiocytosis Secondary to Peripheral T Cell Lymphoma with Rapid Onset and Fatal Progression in a Young Patient: A Case Report and Review of the Literature

Patrycja Paluszkiewicz; Adrian Martuszewski; Maciej Majcherek; Marta Kucharska; Aleksandra Bogucka-Fedorczuk; Tomasz Wróbel; Anna Czyż

doi:10.12659/AJCR.932765

30 September 2021 : Case report Poland

Hemophagocytic Lymphohistiocytosis Secondary to Peripheral T Cell Lymphoma with Rapid Onset and Fatal Progression in a Young Patient: A Case Report and Review of the Literature

Challenging differential diagnosis, Rare disease

Patrycja Paluszkiewicz^1CDEF, Adrian Martuszewski^2CDEF, Maciej Majcherek^3ABCDE*, Marta Kucharska^4BC, Aleksandra Bogucka-Fedorczuk^3CDE, Tomasz Wróbel^3EFG, Anna Czyż^3ABCDEF

DOI: 10.12659/AJCR.932765

Am J Case Rep 2021; 22:e932765

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Table 1. Basic laboratory tests performed during the diagnostic process.

	28th Feb	31st May	3rd Jun	12th Jun	19th Jun	12th Jul
Leucocytes (G/L)	2.43	1.26	5.23	3.76	3.41	1.12
Neutrophils (G/l)	1.24	0.36	3.27	0.78	2.12	0.89
Hemoglobin (g/dL)	14.3	12.4	12.4	11.4	12.7	9.3
Platelets (K/μl)	143	110	103	70	153	15
AlAT (U/l)	54	314	171	80	90	204
AspAT (U/l)	41	260	96	93	87	403
Bilirubin (mg/dL)	nd	1.4	2.1	1.9	0.9	1.7
CRP (mg/l)	0.6	0.7	0,4	1.9	0.5	1.9
LDH (U/l)	453	1,247	658	998	618	2,197
Ferritin (μg/l)	nd	605	nd	nd	nd	78,600
Fibrinogen (g/l)	1.66	1.65	nd	nd	nd	0.39
Triglycerides (mg/dL)	nd	nd	201	nd	nd	318
AlAT – alanine aminotransferase; AspAT – asparagine aminotransferase; LDH – lactate dehydrogenase; CRP - C-reactive protein; nd – no data.

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Hemophagocytic Lymphohistiocytosis Secondary to Peripheral T Cell Lymphoma with Rapid Onset and Fatal Progression in a Young Patient: A Case Report and Review of the Literature

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