11 October 2021>: Articles
Toxic Epidermal Necrolysis Caused by Allopurinol: A Serious but Still Underestimated Adverse Reaction
Rare disease, Adverse events of drug therapy
Daniel Hoyer A* , Carlo Atti A , Sebastian Nuding E , Alexander Vogt E , Daniel G. Sedding E , Artjom Schott ADOI: 10.12659/AJCR.932921
Am J Case Rep 2021; 22:e932921
Table 1. Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) at Day 1, 3, and 5.
Parameters | Points d1/d3/d5 |
---|---|
Age >40 yrs | 1/1/1 |
HF >120 bpm | 1/0/0 |
Malignancy | 0/0/0 |
Initial epidermal detachement >10% | 1/1/1 |
Serum-urea 10 mmol/L | 1/0/0 |
Serum-bicarbonate | 0/0/0 |
Serum-glucose >14 mmol/L | 1/0/0 |
SCORTEN-Points | 5/2/2 |
Mortality (%) | 90%/12%/12% |
Microsoft Excel 2016 (Microsoft Corporation, Redmond, WA, USA). |