11 October 2021
: Case report 
Toxic Epidermal Necrolysis Caused by Allopurinol: A Serious but Still Underestimated Adverse Reaction
Rare disease, Adverse events of drug therapy
Daniel Hoyer1ACDEF*, Carlo Atti1ABCDE, Sebastian Nuding1E, Alexander Vogt1E, Daniel G. Sedding1E, Artjom Schott1ABCDEDOI: 10.12659/AJCR.932921
Am J Case Rep 2021; 22:e932921
Table 2. Predicted mortality based on the Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN).
| Parameters | Points |
|---|---|
| Age >40 yrs | 1 |
| HF >120 bpm | 1 |
| Malignancy | 1 |
| Initial epidermal detachement >10% | 1 |
| Serum-urea 10 mmol/L | 1 |
| Serum-bicarbonate <20 mmol/L | 1 |
| Serum-glucose >14 mmol/L | 1 |
| Scores of 0 and 1 points are associated with 3% mortality; 2 points, 12%; 3 points, 35%; 4 points, 58%; and 5 and more points, 90%. Microsoft Excel 2016 (Microsoft Corporation, Redmond, WA, USA). | |