27 November 2021
: Case report 
Nodular Sclerosing Mesenteritis: An Occasional Finding Mimicking a Spindle Cell Tumor
Challenging differential diagnosis, Rare disease
Giovanna Brancato1AE, Marcello Donati1AE, Lucia Salvatorelli2CF, Gaetano Magro2CD, Michela Zanatta1BE*, Francesca Lentini1BF, Guido Basile1DFDOI: 10.12659/AJCR.933189
Am J Case Rep 2021; 22:e933189
Table 1. Differential diagnosis: Comparative morphological and immunohistochemical features of SM, DF, and GIST.
| Disease | Morphology | α-SMA | CD34 | β-catenin (nuclear expression) | CD117 | DOG1 |
|---|---|---|---|---|---|---|
| SM | Diffuse Staining | No staining | No staining | No staining | No staining | |
| DF | Focal staining | No staining | Diffuse staining | No staining | No staining | |
| GIST | Variable staining | Variable staining | No staining | Diffuse staining | Diffuse staining | |
| SM – sclerosing mesenteritis; DF – desmoid-type fibromatosis; GIST – gastrointestinal stromal tumor; α-SMA – α-smooth muscle actin. | ||||||