Spontaneous Recovery of Hemophagocytic Lymphohistiocytosis Due to Primary Epstein-Barr Virus Infection in an Adult Patient

17 October 2021 : Case report Japan

Unusual clinical course

Yuichiro Matsuo^1ADEF, Keiichi Iwanami^2ADEF*, Eiji Hiraoka^1ADEF, Rentaro Oda^3DE

DOI: 10.12659/AJCR.933272

Am J Case Rep 2021; 22:e933272

Background Case Report Discussion Conclusions References:

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Table 1. Laboratory data.

Laboratory test	Patient value	Reference value
White blood cells (/µL)	9600	4000–8000
Neutrocytes (%)	22.5	45–55
Eosinophils (%)	0.5	0–5
Monocytes (%)	10.5	4–6
Lymphocytes (%)	65.5	25–40
Atypical lymphocytes (%)	1.0	0
Hemoglobin (g/dL)	16.9	14–18
Platelets (/μL)	102 000	150 000–350 000
Total protein (g/dL)	7.4	6.7–8.3
Albumin (g/dL)	3.9	3.1–5.1
Aspartate aminotransferase (IU/L)	385	13–33
Alanine aminotransferase (IU/L)	475	8–42
Lactate dehydrogenase (IU/L)	1298	119–229
Alkaline phosphatase (IU/L)	560	115–359
γ-Glutamyl transferase (IU/L)	195	10–47
Total bilirubin (mg/dL)	12.37	0.2–1.2
Direct bilirubin (mg/dL)	8.92	0.0–0.6
Urea nitrogen (mg/dL)	14.3	8–22
Creatinine (mg/dL)	1.03	0.61–1.04
Sodium (mEq/L)	135	138–146
Potassium (mEq/L)	4.4	3.6–4.9
Chloride (mEq/L)	92	99–109
Calcium (mg/dL)	9.3	8.7–10.3
Phosphorus (mg/dL)	2.9	2.5–4.7
Glucose (mg/dL)	115	70–109
Total cholesterol (mg/dL)	95	128–219
High density cholesterol (mg/dL)	7	41–96
Triglycerides (mg/dL)	306	50–150
Ferritin (ng/mL)	17 211	21–274
Soluble interleukin-2 receptor (IU/mL)	4443	122–496
C-reactive protein (mg/dL)	17.89	0.0–0.29
Erythrocyte sedimentation rate (mm/h)	30	1–10
Antinuclear antibodies	Negative	Negative
Rheumatology factors	Negative	Negative
Fibrinogen (mg/dL)	377	200–400
Prothrombin time (sec)	15.0	12.5
Prothrombin time (INR)	1.27
Activated partial thromboplastin time (sec)	84.8	24–34
D-dimer (g/mL)	1.93	0.0-0.99

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