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08 December 2021: Articles

A Case Series of Adult Patients Diagnosed with IgA Vasculitis Requiring Systemic Immunosuppression

Unusual setting of medical care, Rare disease, Adverse events of drug therapy

Fenfen Cai A , Lisa Phipps A , Peter Wu A , Ming-Wei Lin A*

DOI: 10.12659/AJCR.933407

Am J Case Rep 2021; 22:e933407

Table 1. IgAV cases.

PatientAge/race/sexOrgan involvementBiopsy resultsTherapyOutcomes
131/A/FSkin-abdomen-joints-Skin - leukocytoclastic vasculitis.Kidney – crescentic glomerulonephritis with mesangiocapillary IgAGC, CYC, MMFImproving proteinuria. Improving skin vasculitis
243/I/MSkin-Skin – IgA vasculitisGC, AZTRemission
364/T/FSkin-abdomen-Lung – capillaritis suggestive of vasculitisGC, AZT – refractory, MMF – sepsis, RTX+SIR – remissionDisease remission. Hypogamma-globulinemia.Adrenal insufficiency. Infection, death
A – Aboriginal; I – Indian; T – Turkish; M – male; F – female; GC – glucocorticoids; MMF – mycophenolate; CYC – cyclophosphamide; RTX – rituximab; SIR – sirolimus. Main organ involvement is highlighted in .

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923