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02 November 2021 : Case report  Poland

Glucocorticoids Induce Partial Remission of Focal Segmental Glomerulosclerosis but Not Interstitial Nephritis in COVID-19 Acute Kidney Injury in an APOL1 Low-Risk Genotype White Patient

Challenging differential diagnosis, Rare coexistence of disease or pathology

Piotr J. Nowak1ABCDEF*, Joanna Forycka2BCEF, Natalia Cegielska2BCEF, Karolina Harendarz2BCEF, Małgorzata Wągrowska-Danilewicz3BCD, Marian Danilewicz4BCD, Tomasz Płoszaj5BCD, Maciej Borowiec5CDG, Rafał Wlazeł6BCD, Michał Nowicki1DEG

DOI: 10.12659/AJCR.933462

Am J Case Rep 2021; 22:e933462

Table 1. Summary of blood laboratory evaluations and relevant trends during hospitalization.

Laboratory testReferenceHospital day
1234561117
Creatinine520530570540450320126112
Urea2.8–7.2 mmol/L18.020.322.523.525.024.112.29.7
Potassium3.5–5.1 mmol/L4.14.25.24.55.04.54.34.7
Sodium136–146 mmol/L134135138137138138139140
Chloride101–109 mmol/L99101102104107107109112
Bicarbonates22–26 mmol/L20.820.920.822.623.924.9
Total calcium2.2–2.65 mmol/L1.751.8
Corrected calcium 2.2–2.65 mmol/L2.22.3
Phosphates0.81–1.45 mmol/L1.51.61.7
pH7.35–7.457.407.407.417.377.397.43
Plasma lactate acid0.5–2.2 mmol/L0.80.6
Albumin35–55 g/L22.519.318.3
Total protein66–83 g/L49.446.5
Total cholesterol3–5 mmol/L4.26.1
Triglycerides2.2
Glucose4.1–5.5 mmol/L4.64.5
Total bilirubin5–21 µmol/L4.04.4
ALP30–12 U/L35
ALT41
AST6540
GGT5243
CK13010733
Myoglobin28–72 ng/mL92
LDH510560415
D-dimer0.7
Ferritin30–400 ng/mL3153
Fibrinogen150–450 mg/dL699518
CRP1992583142551236652
Procalcitonin0.430.750.560.150.15
WBC4–11×10/µL11.511.713.08.58.79.711.49.9
Platelet count15–40×10/µL318331391439465483223206
Hemoglobin14–18 g/dL15.313.914.213.713.213.412.511.1
Sars-CoV-2 rRT-PCRDetectedNot detected
Anti-SARS-CoV-2 IgMDetected
Anti-SARS-CoV-2 IgGDetected
ALP – alkaline phosphatase; ALT – alanine transaminase; AST – aspartate transaminase; CK – creatine kinase; CRP – C-reactive protein; GGT – gamma-glutamyltransferase; IgM – immunoglobulin M; IgG – immunoglobulin G; LDH – lactate dehydrogenase; WBC – white blood cells; rRT-PCR – real-time reverse transcription polymerase chain reaction.
* Calcium serum concentration corrected for hypoalbuminemia.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923