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02 November 2021: Articles

Glucocorticoids Induce Partial Remission of Focal Segmental Glomerulosclerosis but Not Interstitial Nephritis in COVID-19 Acute Kidney Injury in an APOL1 Low-Risk Genotype White Patient

Challenging differential diagnosis, Rare coexistence of disease or pathology

Piotr J. Nowak A* , Joanna Forycka B , Natalia Cegielska B , Karolina Harendarz B , Małgorzata Wągrowska-Danilewicz B , Marian Danilewicz B , Tomasz Płoszaj B , Maciej Borowiec C , Rafał Wlazeł B , Michał Nowicki D

DOI: 10.12659/AJCR.933462

Am J Case Rep 2021; 22:e933462

Table 3. Summary of relevant parameters and main treatment during follow-up.

MeasureReferenceWeeks after discharge
41216192343
24-hour proteinuria11.711.46.84.03.60.4
ACR1663
Urine sedimentBlandBlandBlandBland, single hyaline castsBlandBland, single hyaline castsBland
Serum creatinine10110899119115119
CKD-EPI eGFR>60 ml/min/1.73 m837785687168
Serum albumin31–52 g/L26.3
Serum potassium3.5–5.1 mmol/L3.84.33.94.84.84.6
Serum sodium136–146 mmol/L139141142
WBC in blood4–11×10/µL12.613.511.412.09.57.3
Platelet count15–40×10/µL196264235210218234
Blood hemoglobin14–18 g/dL14.416.716.915.215.413.7
Arterial blood pressure 135/75139/81136/82138/85130/79128/76
Body weight [kg]969998989997
BMI 18.5–25 kg/m27.728.628.328.328.628
Prednisone dose [mg/day]60606060→50405
Cyclosporine dose [mg/day]NoneNoneNone400 400400→300
Enalapril dose [mg/day]2020→3030303030
Nebivolol dose [mg/day]2.52.52.52.5→555
Kidney re-biopsyYes
ACR – albumin/creatinine ratio; CKD-EPI eGFR – chronic kidney disease epidemiology collaboration estimated glomerular filtration rate; WBC – white blood cells; BMI – body mass index.
* Average home blood pressure from previous week;
** patient’s muscle mass was above the average;
*** therapy initiation; → dose change.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923