06 March 2022>: Articles
The Missing Link: A Case of Severe Adverse Reaction to Histamine in Food and Beverages
Unknown etiology, Challenging differential diagnosis
József Tamasi A* , Zsuzsanna Balla B , Dorottya Csuka B , László Kalabay * , Henriette Farkas *DOI: 10.12659/AJCR.934212
Am J Case Rep 2022; 23:e934212
Table 2. Laboratory tests for hereditary angioedema.
Laboratory tests | Symptom-free state | Follow-up testing | Reference values |
---|---|---|---|
Complement, Total (CH50) | 58.8 U/ml | 61 U/mL, 69 U/mL | 48–103 U/mL |
C1q concentration | 85 mg/L, 94 mg/L | 60–180 mg/L | |
Complement C3 concentration | 1.0 g/L | 0.92 g/L, 0.97 g/L | 0.90–1.80 g/L |
Complement C4 concentration | 0.12 g/L | 0.10 g/L, 0.11 g/L | 0.15–0.55 g/L |
C1 inhibitor concentration | 0.14 g/L, 0.22 g/L | 0.15–0.30 g/L | |
C1 inhibitor activity | 110%, 79% | 70–110% | |
Anti-C1INH (IgG) | 0.03 mU/L, 0.00 mU/L | 0.00–2.00 mU/L | |
Anti-C1INH (IgA) | 0.00 mU/L, 0.00 mU/L | 0.00–0.60 mU/L | |
Anti-C1INH (IgM) | 0.43 mU/L, 0.83 mU/L | 0.00–12.00 mU/L | |
Anti-C1q (IgG) | 164 mU/L, 92 mU/L | 0–52 mU/L | |
C1-INH (SERPING1) bi-directional Sanger sequence analysis | Negative | ||
Bi-directional sequencing for mutations of plasminogen in exon 9 | Negative | ||
Bi-directional sequencing for mutations of factor XII in exon 9 (Thr309Lys and Thr309Arg) | Negative |