Histiocytic Disorder Mimicking a Brain Tumor: A Report of 2 Rare Cases

16 August 2022: Articles

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease

Frances Xiuyan Feng ^B , Negin Farsi ^B , Min Dai ^B , Areli K. Cuevas-Ocampo ^A , Diana M. Veillon ^A , James D. Cotelingam ^A*

DOI: 10.12659/AJCR.935885

Am J Case Rep 2022; 23:e935885

Table 1. 2016 Revised classification of histiocytosis and neoplasms of the macrophage-dendritic cell lineages.

	Indeterminate cell histiocytosis (ICH)Erdheim Chester diseases (ECD)
	Cutaneous non-LCH Xanthogranuloma (XG)Family Juvenile xanthogranuloma (JXD) Adult xanthogranuloma (AXD) Solitary reticulohistiocytoma (SRH) BCH GEH Progressive nodular histiocytosis (PNH) Non-XG family Cutaneous Rosia-Dorfman Disease (RDD) Necrobiotic xanthogranuloma (NXG) Other NOSCutaneous non-LCH with a major systemic component XG family Non-XG family
	Familial Rosai-Dorfman DiseaseSporadic RDD Classical RDD Extra-nodal RDD RDD with neoplasia or immune disease Unclassified
	Primary Malignant HistiocytosesSecondary Malignant Histiocytoses
	Primary Histiocytoses of the H group (HLH): Mendelian inherited conditions leading to HLHSecondary HLH (non-Mendelian HLH)HLH of unknown/uncertain origin
It is adapted from: “Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages” by Emile JF, et al. Blood. 2016; 127(22): 2672–2681.