01 April 2022: Articles
A Case of Hemophagocytic Lymphohistiocytosis (HLH) Secondary to T Cell Lymphoma and Cytomegalovirus (CMV) Infection and Complicated by Tumor Lysis Syndrome (TLS)
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Yassine Kilani A* , Trisha Laxamana B , Kamran Mahfooz B , Mubarak H. Yusuf B , Victor Perez-Gutierrez A , Nehad Shabarek EDOI: 10.12659/AJCR.935915
Am J Case Rep 2022; 23:e935915
Table 1. Summary of the laboratory findings in our patient.
| Unit | Day 1 | Day 5 | Day 8 | Day 11 | Day 13 | |
|---|---|---|---|---|---|---|
| Hemoglobin | g/dL | 11.1 | 7.6 | 8.2 | 8.7 | 4.5 |
| MCV | fL | 84.3 | 85.8 | 87.3 | 86.6 | 100.6 |
| Platelets | ×10/uL | 43 | 83 | 76 | 86 | 38 |
| WBC | ×10/uL | 5.74 | 7.00 | 5.33 | 7.21 | 7.15 |
| Neutrophils | % | 73.4 | 81.9 | 89.2 | 92 | 63.1 |
| LDH | U/L | 1193 | 1908 | 1399 | 1298 | – |
| Fibrinogen | U/L | 80 | – | 290 | – | – |
| Procalcitonin | ng/mL | 1.85 | 6.49 | 5.79 | 7.03 | 5.55 |
| Ferritin | ng/mL | 21 400 | – | – | – | – |
| Triglycerides | mg/dL | – | 250 | 272 | 238 | 343 |
| Sodium | meq/L | 155 | 149 | 139 | 140 | 129 |
| Chloride | meq/L | 120 | 116 | 101 | 101 | 91 |
| Potassium | meq/L | 5.4 | 4.2 | 4.4 | 4.8 | 7.0 |
| BUN | mg/dL | 126 | 131 | 79 | 84 | 66 |
| Creatinine | mg/dL | 3.87 | 5.79 | 5.14 | 5.93 | 5.78 |
| Bicarbonates | mg/dL | 18 | 14 | 18 | 18 | 4 |
| Anion Gap | mg/dL | 17 | 19 | 20 | 21 | 34 |
| Phosphorus | mg/dL | 7.3 | 9.4 | 9.1 | 11.0 | 16.1 |
| Calcium | mg/dL | 8.2 | 6.3 | 7.0 | 7.8 | 6.3 |
| Uric acid | mg/dL | 13 | 9,6 | – | – | 11.0 |
| AST | U/L | 151 | 146 | 69 | – | 1862 |
| ALT | U/L | 56 | 39 | 42 | – | 1191 |
| ALP | U/L | 196 | 191 | 158 | – | 81 |