14 April 2022
: Case report 
Waterhouse-Friderichsen Syndrome with Bilateral Adrenal Hemorrhage Associated with Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia in an Adult Patient with History of Intravenous Drug Use
Unusual clinical course, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Thomas Kalinoski1EF*DOI: 10.12659/AJCR.936096
Am J Case Rep 2022; 23:e936096
Table 1. Comparison of clinical characteristics of published cases involving Staphylococcus aureus-associated adrenal hemorrhage.
| Source | Age | Sex | Outcome | Organism diagnosis | Methicillin susceptibility | Adrenal hemorrhage diagnosis | Endocrine Testing | Source Infection | Rash | Coagulopathy |
|---|---|---|---|---|---|---|---|---|---|---|
| Tormos []13 | 2 yrs | Male | Death | Blood culture, postmortem | Resistant | Autopsy | No | Pneumonia | - | - |
| 34 yrs | Male | Death | Blood culture, premortem | Susceptible | Autopsy | No | Myositis | - | - | |
| Guarner []14 | – | – | Death | Antibody, postmortem | Unknown | Autopsy | No | – | – | – |
| – | – | Death | Antibody, postmortem | Unknown | Autopsy | No | – | – | – | |
| – | – | Death | Antibody, postmortem | Unknown | Autopsy | No | – | – | – | |
| – | – | Death | Antibody, postmortem | Unknown | Autopsy | No | – | – | ||
| Adem []15 | 15 mos | Female | Death | Blood culture, premortem | Susceptible | Autopsy | No | Pneumonia | Yes | Yes |
| 9 mos | Female | Death | Respiratory culture, premortem | Resistant | Autopsy | No | Pneumonia | Yes | Yes | |
| 17 mos | Male | Death | Respiratory culture, premortem | Resistant | Autopsy | No | Pneumonia | Yes | Yes | |
| Mukherjee []16 | 7 yrs | Male | Death | Blood culture, premortem | Susceptible | Adrenal ultrasound | No | Cellulitis | Yes | Yes |
| “–“ indicates that parameter was not indicated in cited article. | ||||||||||