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15 August 2022: Articles

Degenerated Serous Cystic Tumor of the Pancreas: Case Report and Literature Review of an Aggressive Presentation of a Benign Tumor

Challenging differential diagnosis, Rare coexistence of disease or pathology

Xenofon Papazarkadas A , Eleftherios Gialamas A* , Galab M. Hassan A , Roland Chautems B , Aurelie Bornand A , Giacomo Puppa A , Christian Toso A

DOI: 10.12659/AJCR.936165

Am J Case Rep 2022; 23:e936165

Table 1. Studies involving degenerated serous cystadenomas of the pancreas and selected treatment.

Author/YearSymptoms/signsLocalizationMalignant feature(s)Surgical treatmentOutcome
Kameh et al, 1991 []11 JaundiceHeadFocal perineural invasionTotal pancreatectomyNot disclosed
Ohta et al, 1993 []12 Incidental findingBodyVascular and perivascular invasionEnucleationCured
Widmaier et al, 1996 []13 Abnormal liver testsHeadLymph node metastasisPylorus-preserving partial duodenopancreatectomyCured
Abe et al, 1998 [14]Palpable mass at the left hypochondriumBody and tailLymph node invasionDistal pancreatectomy with splenectomyCured
Friebe et al, 2005 [15]Anorexia, weight loss, abdominal painBody and tailSpleen invasionDistal pancreatectomy with splenectomyCured
Matsumoto et al, 2005 [16]Palpable mass at the left hypochondriumTailSpleen and colonic mesentery invasion, Single lymph node metastasisDistal pancreatectomy, splenectomy, and segmental resection of the colonCured
Shintaku et al, 2005 [17]Fatigue and diarrheaBody and tailSpleen and neural invasionDistal gastrectomy, distal pancreatectomy with splenectomyNot disclosed
King et al, 2009 [18]Gastric bleeding and abdominal painHeadDuodenal invasionPancreaticoduodenectomyCured
Cho et al, 2011 [19]HematocheziaTailSpleen and transverse colon invasionDistal pancreatectomy, splenectomy, and segmental resection of the colonNot disclosed
Kadhirvel et al, 2015 [20]Abdominal painBody and tailSpleen invasion by contiguityDistal pancreatectomy with splenectomyNot disclosed
Gao et al, 2016 [21]Back painBodySpleen vein encasementDistal pancreatectomy and splenectomyNot disclosed
Kawai et al, 2020 [22]Palpable mass at the left hypochondriumHeadSuperior mesenteric vein invasionPancreaticoduodenectomy with resection of limited superior mesenteric veinLiver and peritoneal metastases after 4 years
Yagi et al, 2020 [23]Diabetes mellitusTailSpleen invasionLaparoscopic distal pancreatectomy with splenectomyCured

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923