08 June 2022: Articles
Rhabdomyolysis and Acute Kidney Injury Associated with Infection: A Report of 2 Cases
Management of emergency care, Rare disease
In Hee Lee A* , Dong Jik Ahn BDOI: 10.12659/AJCR.936407
Am J Case Rep 2022; 23:e936407
Table 1. Laboratory findings on admission and clinical courses of patients.
| Variable | Reference range | Case 1 | Case 2 |
|---|---|---|---|
| Age (years)/Gender | 69/Male | 62/Male | |
| Complete blood count | |||
| White blood cell (/μL) | 3,600–9,600 | 6,700 | 5,400 |
| Hemoglobin (g/dL) | 11.5–15.5 | 15.9 | 15.5 |
| Platelets (×10/μL) | 140–380 | 198 | 177 |
| ESR (mm/hour) | 0–10 | 21 | 59 |
| Serum biochemistry | |||
| Albumin (g/dL) | 3.5–5.1 | 3.9 | 4.0 |
| Blood urea nitrogen (mg/dL) | 8.0–23.0 | 46.8 | 67.4 |
| Creatinine (mg/dL) | 0.5–1.2 | 4.8 | 8.8 |
| eGFR (mL/min/1.73 m) | >90 | 11 | 6 |
| AST/ALT (U/L) | 703/131 | 243/235 | |
| CK (U/L) | 30–180 | 32,225 | 10,590 |
| LDH (U/L) | 1,363 | 1,309 | |
| Calcium (mg/dL) | 8.2–10.2 | 8.1 | 8.9 |
| Myoglobin (ng/mL) | 28–72 | 13,315 | 1,656 |
| C-reactive protein (mg/L) | 349.9 | 317.2 | |
| Lactate (mmol/L) | 0.7–2.1 | 4.8 | 2.8 |
| Arterial blood gas analysis | |||
| pH | 7.35–7.45 | 7.48 | 7.29 |
| PaO(mmHg) | 72–104 | 103 | 87.5 |
| PaCO (mmHg) | 32–45 | 17.3 | 24.5 |
| HCO(mEq/L) | 22–30 | 13 | 12 |
| Anion gap (mmol/L) | 7–16 | 23.5 | 29.3 |
| Urine myoglobin (ng/mL) | 651 | 55.1 | |
| FE (%) | 8.09 | 7.24 | |
| McMahon risk score | 11 | 12.5 | |
| Renal replacement therapy | None | Hemodialysis | |
| Hospitalization | 14 days | 12 days | |
| Duration of antibiotic therapy | 17 days | 19 days | |
| Clinical outcome | Survived | Survived | |
| * Calculated by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation; ** corrected for serum albumin. ESR – erythrocyte sedimentation rate; eGFR – estimated glomerular filtration rate; AST – aspartate aminotransferase; ALT – alanine aminotransferase; CK – creatine kinase; LDH – lactate dehydrogenase; FE – fractional excretion of sodium. | |||