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07 October 2022: Articles

Demodicosis as a Skin Complication in Organ Transplant Recipients: A Case Series

Rare coexistence of disease or pathology

Adriana Marquardt-Feszler A* , Maria Alicja Dębska-Ślizień C , Beata Imko-Walczuk A

DOI: 10.12659/AJCR.936467

Am J Case Rep 2022; 23:e936467

Table 1. Characteristics of studied patients.

Case 1Case 2Case 3Case 4
Age and gender79 M64 M70 M68 M
Original kidney diseaseGlomerulonephritis, DM2AgenesisDM1Glomerulonephritis
Time since transplantation to diagnosis of demodicosis10 years6 years8 years6 years
Daily doses of immunosuppressionMMF – 250 mgTAC – 1 mgMP – 4 mgTAC – 2 mgMP – 4 mgMMF – 500 mgCsA – 125 mgP – 5 mgMMF – 1500 mgTAC – 2 mgP – 5 mg
Skin type []25 IIIIIII
Diagnostic methodMicroscopic evaluation of scrapings of the face
Type of skin lesions and symptomsItch, pustules, papules and telangiectasiasItch, dryness and rednessItchItch, burning, telangiectasias
Additional skin lesionsBCC, actinic keratosis, seborrheic keratosisBCCBCC, actinic keratosisBCC, actinic keratosis, seborrheic keratosis
TreatmentTI 10 mg/g, TP 5%TI 10 mg/g, TP 5%TI 10 mg/g, TP 5%TI 10 mg/g, TP 5%
Time of therapy to full resolution8 weeks8 weeks16 weeks8 weeks
BCC – basal cell carcinoma; CsA – cyclosporin A; DM1 – diabetes mellitus type 1; DM2 – diabetes mellitus type 2; DM – Demodex mites; M – male; MMF – mycophenolate mofetil; MP – methylprednisone; P – prednisone; TAC – tacrolimus; TI – topical ivermectin; TP – topical permethrin.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923