27 July 2022
: Case report 
Hypoprothrombinemia During Cefmetazole Treatment: A Case Report
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Yuichiro Haba1ABCDEF*, Hikaru Akizuki2ABCDEF, Naoyuki Hashiguchi2ADEF, Toshio Naito
1ADEF
DOI: 10.12659/AJCR.936712
Am J Case Rep 2022; 23:e936712
Table 1. Laboratory findings on the first visit, on admission, and on the 6th hospital day.
| First visit | Admission | 6th hospital day | Reference range in our hospital | |
|---|---|---|---|---|
| WBC (/μL) | 12 700 | 18 800 | 6200 | 3600–8900 |
| Hb (g/dL) | 11.6 | 11.4 | 11.5 | 11.1–15.2 |
| PLT×10 (/μL) | 28.0 | 13.1 | 37.4 | 15.3–34.6 |
| T-Bil (mg/dL) | 0.48 | 0.71 | 0.28 | 0.40–1.20 |
| AST (U/L) | 17 | 17 | 18 | 5–37 |
| ALT (U/L) | 14 | 15 | 15 | 6–43 |
| ALP (U/L) | – | 143 | 130 | 110–348 |
| γ-GT (U/L) | 10 | 10 | 11 | 0–75 |
| LD (U/L) | 219 | 161 | 173 | 119–221 |
| UN (mg/dL) | 20 | 16 | 12 | 9–21 |
| Cr (mg/dL) | 0.90 | 0.96 | 0.70 | 0.50–0.80 |
| Ccr (mL/min) | 52.5 | 49.2 | 66.0 | |
| CRP (mg/dL) | 0.61 | 15.17 | 1.16 | 0–0.29 |
| APTT (s) | – | 31.3 | 38.5 | 20.0–38.0 |
| PT (s) | – | 13.0 | 37.1 | 13.8 |
| PT-INR | – | 0.95 | 2.46 | 0.90–1.10 |
| Ccr – creatinine clearance | ||||