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24 September 2022 : Case report  USA

Severe Pancytopenia After COVID-19 Revealing a Case of Primary Bone Marrow Diffuse Large B Cell Lymphoma

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)

Yassine Kilani ORCID logo1ABDEFG*, Haris Sohail1BEFG, Chee Yao Lim ORCID logo1BEG, Alyssa Payette1EF, Syeda Ashna Fatima Kamal1EG, Afsheen Afzal1EFG, Toqeer Khan1EFG, Nushra Paracha1EG, Monica Reddy Muppidi2ADEG, Daniel Sittler1DE

DOI: 10.12659/AJCR.937500

Am J Case Rep 2022; 23:e937500

Table 1. Complete blood count (CBC). The bicytopenia found at the patient’s previous admission progressed into pancytopenia in the setting of COVID-19. Note that the patient had normocytic anemia and thrombocytopenia 1 month prior to admission.

Range & unit2 months prior (Baseline)1 month prior (previous admission)Day 1Day 3Day 5Day 7Day 9Day 11
Platelets150–450×10/mcL2271191437753211312
White blood cells4.80–10.80×10/mcL6.746.548.002.651.840.630.420.37
Red blood cells4.70–6.10×10/mcL4.103.213.182.623.662.812.192.51
Hemoglobin14.0–18.0 g/dL11.48.78.16.59.37.25.66.4
Hematocrit42.0–52.0%34.825.224.120.028.222.018.019.3
MCV80.0–99.0 fL84.978.575.876.377.078.382.276.9
MCH27.0–31.0 fL27.827.125.524.825.425.625.625.5
RDW12.0–15.0%13.815.217.117.217.217.217.317.4
Neutrophils44.0–70.0%64.547.248.949.522.36.411.816.2
Lymphocyte20.0–45.0%24.224.329.834.764.176.278.670.3
Monocyte2.0–10.0%22.827.120.014.710.99.54.88.1
Eosinophil1.0–4.0%0.40.00.00.00.00.00.00.0
Basophil0.2–1.8%0.40.50.30.01.10.00.00.0
Immature granulocytes0.0–0.2%0.70.91.01.11.67.94.85.4

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923