10 October 2022>: Articles
Myxoid Liposarcoma of the Vulva: A Rare Malignancy Mimicking Benign Vulvar Mass
Challenging differential diagnosis, Rare disease
Dodi Suardi A , Zafli Hamdani B , Ivonne Golda Palungkun B , Jessica Kireina A , Kemala Isnainiasih Mantilidewi A*DOI: 10.12659/AJCR.937575
Am J Case Rep 2022; 23:e937575
Table 1. Reported cases of vulvar liposarcoma in English literature.
Case | Author | Age | Location | Subtype | Initial treatment | Surgical margin | Recurrence | Outcome |
---|---|---|---|---|---|---|---|---|
1 | Taussig et al []3 | 29 | Left LM | Unknown | HVE | n/a | 2 months | DOD (5 months) |
2 | Gondos et al []4 | 38 | Left perineum | Pleomorphic | WE | Negative | 8 months | NED (8 years) |
3 | Brooks et al []5 | 15 | Perineum | Myxoid | WE | n/a | 20 months | DOD (31 months) |
4 | Genton et al []6 | 60 | Left LM | Well-differentiated | LE | n/a | (–) | NED (10 months) |
5 | Rogers et al []7 | 65 | Left LM | Pleomorphic | LE | n/a | Unknown | Unknown |
6 | Nucci et al []8 | 61 | Right LM | Well-differentiated | LE | Negative | (–) | NED (7 years) |
7 | Nucci et al []8 | 44 | Right LM | Well-differentiated | LE | Negative | (–) | Unknown |
8 | Nucci et al []8 | 46 | Right LM | Well-differentiated | LE | Negative | (–) | NED (1 year) |
9 | Nucci et al []8 | 28 | LM | Well-differentiated | LE | Negative | (–) | NED (14 months) |
10 | Nucci et al []8 | 69 | Clitoris | Well-differentiated | LE | Negative | (–) | NED (18 months) |
11 | Nucci et al []8 | 59 | Left LM | Well-differentiated | LE | Positive | 10 years | NED (31 months) |
12 | Yokouchi et al []9 | 21 | Left LM | Well-differentiated | LE RT | Positive | (–) | NED (18 months) |
13 | Donnellan et al []10 | 26 | Left LM | Myxoid | WE | Negative | (–) | NED (9 months) |
14 | AshrafGanjooie []11 | 65 | Left LM | Well-differentiated | LE | n/a | Unknown | Unknown |
15 | Wu et al []12 | 45 | Right LM | Myxoid | LE | n/a | 16 months | NED (28 months) |
16 | Baek et al []13 | 33 | Bilateral LM | Myxoid | WE | Negative | (–) | NED (2 years) |
17 | Schoolmeester et al []15 | 34 | Left LM | Myxoid | LE | Negative | (–) | NED (2 months) |
18 | Schoolmeester et al []15 | 66 | Vulva –Unspecified | Well-differentiated | LE | Negative | (–) | NED (25 months) |
19 | Kwak et al []1 | 37 | Bilateral LM | Well-differentiated | LE RT | Positive | (–) | NED (44 months) |
20 | Redroban et al []14 | 53 | Right LM | Myxoid | LE | n/a | Unknown | Unknown |
21 | Kaur et al []16 | 30 | Right LM | Myxoid | LE | Negative | (–) | NED (8 years) |
22 | Current case | 39 | Left LM | Myxoid | LE | Negative | (–) | NED (4 months) |
LM – labium majus; HVE – hemivulvectomy; WE – wide excision; LE – local excision; DOD – dead of disease; NED – no evidence of disease; n/a – not available. |