21 December 2022: Articles
Masson Tumor of the Central Nervous System: A Case Report and Review of Literature
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Rare disease
Fatemeh Mohammadyari A* , Tarek Dufan D , Yasin K. Ahmed D , Parviz Dolati BDOI: 10.12659/AJCR.937597
Am J Case Rep 2022; 23:e937597
Table 1. Demographic, clinical, radiological, and result of treatment for 45 previously published cases of IPEH, including our current case.
| Author | Age, sex | Clinical sign | Brain site | Imaging findings | History of RT/dose (gray)/interval between RT and IPEH appearance (years) | Surgical resection | Result |
|---|---|---|---|---|---|---|---|
| Lesley WS et al [], 200028 | 46 y, F | Dysphagia, otalgia, head and neck pain | Right posterior inferior-PICA aneurysm (type 2) | MRI: enhanced T1 hypointense, T2 hyperintense massMRA: faint vascular lesion | No | Complete | No recurrence at 1 year |
| Stoffman MR et al [], 200329 | 54 y, F | Dysarthria, dysphagia | Meckle’s cave (type 1) | MRI: extradural hemorrhagic lesionCT: unenhanced temporal mass with hyperdense blood | No | Subtotal | Residual tumor at 10 mo |
| Du Plessis DG et al [], 200330 | 6 y, F | Skull bump | Parietal, frontal lobes (extravascular) | MRI: subcortical enhancing lesion | No | Complete | No recurrence at 1 year |
| Lee W et al [], 200431 | 46 y, M | Dizziness, hypoesthesia of upper limb | Giant V4 aneurysm (type 2) | MRI: T1 isointense, T2 hypointense massMRA: no obvious flow signal within the lesion | No | No surgery | Asymptomatic at 2 years |
| Cagli S et al [], 20041 | 16 y, F | Diplopia, ptosis | Cavernous sinus (type 1) | MRI: enhanced T1 hyperintense lesion | No | Subtotal | Small residual mass at 3 years |
| 18 y, F | Diplopia | Cavernous sinus (type 1) Parietal lobe (type 2) | MRI: enhanced T1 isointense, T2 hyperintense lesion | NoNoNo | SubtotalTotalTotal | Evidence of residual mass at 3 years | |
| 24 y, F | Headache, seizure | Cavernous sinus, | MRI: enhanced T1 isointense, T2 hyperintense lesion | No recurrence at 2 years | |||
| 28 y, F | Diplopia, ptosis | Meckle’s cave (type 1) | MRI: enhanced T1 isointense, T2 hyperintense lesion | No evidence of residual mass at 2 years | |||
| Zhang R et al [], 200519 | 49 y, F | Facial paralysis, hearing loss | Petrous, jugular regions (type 1) | MRI: T1 and T2 hyperintense massCT: hypodense lesion | No | Subtotal | No follow-up available |
| Ohshima T et al [], 200532 | 41 y, F | Diplopia | Middle cranial fossa (type 1) | No | Subtotal | No recurrence at 2 years | |
| Crocker M et al [], 200714 | 43 y, F | Headache | Parietal lobe (type 1) | MRI: enhanced T1 massMRA: AVM in vermis | Yes/SRS 22.5 Gy, 20 Gy/4 | Total | Resection 7 years after radiation therapy, no recurrence at 1 year |
| Witt P et al [], 200833 | 23 y, M | Generalized tonic-clonic seizure | Frontal lobe (extravascular) | MRI: Non-enhanced T1 and T2 hypointense lesion MRA: no evidence of vascular abnormality or neoplasmCT: hemorrhagic lesion | No | Total | No follow-up available |
| Mann P et al [], 2008–201634 | 4 y, F | Parietal lobe (extravascular) | MRI: Subdural lesion with extra-axial fluid | Yes/WBRT 54.7 Gy, 1-year-interval | |||
| 70 y, F | Temporal lobe | MRI: enhanced T1 mass with significant edema | Yes/WBRT 61.6 Gy/15 | ||||
| 44 y, M44 y, M | CerebellumCerebral (extravascular) | MRI: Large enhancing T1 lesion | NoYes/SRS38.0 Gy/10 | ||||
| 31 y, F | Frontal lobe (type 2) | MRI: nodular mass and multifocal calcifications secondary to previous radiation therapy | Yes/External beam/17 | ||||
| 63 y, M | Occipital lobe (extravascular) | MRI: lesion containing blood products | Yes/WBRT30 Gy, SRS/3Yes/External beam (for prior ependymoma & glioblastoma)/12 | ||||
| 33 y, M | Cerebellum (type 2) | MRI: Large enhancing T1 lesion | |||||
| 57 y, M | Language disturbance, tunnel vision, headache | Parietal lobe (extravascular) | CT: normal | No | |||
| Shih C-S et al [], 20127 | 2 d, M | Proptosis | Cerebellum, suprasellar, orbit (type 2) | MRI: enhanced T1 isointense, T2 hyperintense mass | No | Subtotal | Sudden death after 15 mo |
| Karam- chandani J et al [], 20124 | 44 y, M | Headache, disorientation | Temporal lobe (extravascular) | MRI & MRA: posteroinferior AVMCT: hemorrhagic lesion | Yes/SRS 25 Gy in a min dose of 22.8 Gy and max dose of 49.8 Gy/4 | TotalTotalTotalPartial | Resection was performed 4 years after radiation therapy, no recurrence after 30 mo |
| 57 y, M | Vomiting, weakness, headache | Cerebellar (extravascular) | MRI: hemorrhagic mass | Yes/SRS dose unknown/4 | Resection was performed 3 years after radiation therapy, no recurrence after 20 mo | ||
| 67 y, M | Temporal lobe (extravascular) | MRI: enhancing mass of the cavernous sinus | Yes/SRS20 Gy/4Yes/SRS | No recurrence 15 mo after resection | |||
| 73 y, M | Cavernous sinus (extravascular/ intratumoral) | MRI: heterogeneous enhancing mass | 25 Gy/2-month-interval | No follow-up available | |||
| Park KK et al [], 201235 | 10 y, F | Frontal lobe | MRI: enhanced T1 hypointense, T2 hyperintense mass | No | Complete | No recurrence at 8 mo | |
| Taiwo F et al [], 201336 | 72 y, M | Dizziness, lethargy | Frontal lobe (extravascular) | MRI: hemorrhagic lesionCT: enhancing hyperdense mass | No | Subtotal | No residual massAt 2 weeks |
| Miller TR et al [], 201337 | 39 y, F | Syncope | Petrous apex (type 1) | MRI: enhanced T1 hypointense, T2 hyperintense mass | No | Total | Unremarkable course at 3 mo |
| 56 y, F | Sinus infection | Clivus (type 1) | MRI: enhanced T2 hyperintense mass | No | Biopsy | Asymptomatic at 2 years | |
| 73 y, M | Seizure, aphasia | Frontal lobe (type 2) | MRI: enhancing massCT: hyperdense mass | Yes/SRS following AVM | Total | No evidence of residual mass at 6 mo | |
| Ginat DT et al [], 201438 | 72 y, F | Cerebellar dysfunction | Cerebellar (extravascular) | MRI: enhancing lesionCT: hyperattenuating mass | Yes/External beam 5400 cGy/1 | Total | No follow-up available |
| Shah HC et al [], 201439 | 3 mo, M | Swollen scalp | Parietal lobe (type 1) | MRI: T1 isointense, T2 hyperintense mass | No | Total | No recurrence at 1 year |
| Sim SY et al [], 201516 | 11 y, M | Sight-impaired | Parasellar (type 1) | MRI: enhanced T1 isointense, T2 hyperintense massCT: hyperdense mass | Yes/Chemo RT 50’4 Gy/ (RT as an adjuvant therapy) | Total | No recurrence at 13 years |
| Salaud C et al [], 201740 | 56 y, F | Dizziness, aphasia, headache | Temporal lobe (type 1) | MRI: enhanced T1 hypointense, T2 hyperintense massCT: hypodense mass | No | Complete | No recurrence at 5 years |
| Charalambous LT et al [], 201741 | 22 y, M | Headache, inattention | Pineal gland (type 1) | MRI: enhanced hyperdense mass | No | Total | No recurrence after 2 surgery at 3 years |
| Bagga V et al [], 201742 | 24 y, M | Headache, confusion | Frontal lobe (type 1) | MRI and CT: small enhancing lesion | No | Subtotal | No follow-up available |
| Barritt AW et al [], 201743 | 59 y, F | Epilepsy, hallucination | Temporal lobe | MRI: midline shift | Yes/Gamma knife radiosurgery 25 Gy/15 | Subtotal | No recurrence at 18 mo |
| Prat GP et al [], 20183 | 51 y, F | Hydrocephalus, diplopia | Cavernous sinus (type 1) | MRI: enhancing mass | Yes/RT 54 Gy/ (RT as an Adjuvant therapy) | Subtotal | Residual mass at 3 mo |
| Sankey EW et al [], 201944 | 32 y, F | Aphasia | Parietal, frontal lobes | MRI: enhanced lesion within hemorrhage | No | Total | No follow-up available |
| Mezmezian MB et al [], 202045 | 59 y, F | Headache, vertigo | Petrous apex, clivus | MRI: enhanced T1 hypointense, T2 hyperintense massCT: lytic lesion | No | Partial | No recurrence at 30 mo |
| Retzlaff AA et al [], 202046 | 28 y, F | Visual aura, headache, hydrocephalus | Pineal region | MRI: non-enhanced T1 hypointense, T2 hyperintense mass | No | Total | No residual lesion at 9 mo |
| Gajaria PK et al [], 202147 | 45 y, M | Headache, low sharp sight | Cavernous sinus | MRI: enhanced T1 hyperintense mass | No | Complete | Symptom free at 8 mo |
| Manoranjan B et al [], 202148 | 79 y, F | Dizziness, incontinence | Ventricle | No | |||
| Goyal-Honavar A et al [], 202249 | 31 y, F | Headache, ophthalmoplegia | Cavernoussinus | MRI: enhanced T2 hyperintense mass with a component in the sella | Yes/SRS 13 Gy, 2.8 Gy/5 | Partial | Recurrence at 8 mo |
| Present case | 65 y, F | Headache, nausea, vomiting | Right temporal lobe | MRI; T1 Hypo and T2 Hyperintense large mass with gadolinium enhancement and significant brain edema and mass effect | Yes/SRS25 GY/5 | Complete | 12 mo follow-up, no recurrence |
| AVM – arteriovenous malformation; Chemo – chemotherapy; CT – computed tomography; d – days old; F – female; M – male; mo – months old; mo – months; MRA – magnetic resonance angiography; MRI – magnetic resonance imaging; PICA – posterior inferior cerebellar artery; RT – radiotherapy; SRS – stereotactic radiosurgery; T1 – T1-weighted; T2 – T2-weighted; y – years old. | |||||||