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08 October 2022: Articles

Lupus Anticoagulant-Hypoprothrombinemia Syndrome and Pseudotumor Cerebri as an Initial Presentation of Systemic Lupus Erythematosus in a 16-Year-Old Male Patient: A Case Report and Literature Review

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Rare coexistence of disease or pathology

Mohamed H. Omer D , Hind Salama A* , Asim M. Alghaythi B , Abdullah A. Alharbi B , Ghassan AlJohani A

DOI: 10.12659/AJCR.938051

Am J Case Rep 2022; 23:e938051

Table 2. 1: 1 Mixing study of PT and PTT along with lupus anticoagulant detection tests.

TestInitial presentationReference ranges (units)
Prothrombin time (control)51.109.38–12.34 (seconds)
Prothrombin time (mix)15.60
Partial thromboplastin time (control)112.5024.8–32.6 (seconds)
Partial thromboplastin time (mix)95.30
LA1156.8030.00–40.00 (seconds)
LA292.2026.50–32.50 (seconds)
LA1/LA2 ratio1.70∼1.4 Positive
Lupus AnticoagulantPositiveNA
LA1 – lupus anticoagulant screen using dilute Russell’s Viper Venom screening; LA2 – lupus anticoagulant screen using confirmatory reagents.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923