04 April 2023: Articles
Recurrent Reversible Stroke-Like Encephalopathy After 5-Fluorouracil (5-FU) Chemotherapy: A Case Report and Literature Review
Unusual clinical course, Mistake in diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Clinical situation which can not be reproduced for ethical reasons
Kurniawan Agung Yuwono A , Susanna Hilda Hutajulu A , Abdul Gofir B , Dhite Bayu Nugroho B*DOI: 10.12659/AJCR.938437
Am J Case Rep 2023; 24:e938437
Table 2. Adverse drug reactions (ADRs) probability scale.
| To assess the adverse drug reaction, please answer the following questionnaire and give the pertinent score. | |||||
|---|---|---|---|---|---|
| 1 | Are there previous conclusive reports on this reaction? | ||||
| 2 | Did the adverse event appear after the suspected drug was administered? | ||||
| 3 | Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | ||||
| 4 | Did the adverse reaction reappear when the drug was readministered? | ||||
| 5 | Are there alternative causes (other than the drug) that could on their own have caused the reaction? | ||||
| 6 | Did the reaction reappear when a placebo was given? | ||||
| 7 | Was the drug detected in the blood (or other fluids) in concentrations known to be toxic? | ||||
| 8 | Was the reaction more severe when the dose was increased, or less severe when the dose was decreased? | ||||
| 9 | Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | ||||
| 10 | Was the adverse event confirmed by any objective evidence? | ||||