18 March 2023: Articles
Thrombosis with Thrombocytopenia Syndrome (TTS) After ChAdOx1 nCoV-19 Immunization: An Investigative Case Report
Unusual clinical course
Nityanand Jain A* , Piyush Chaudhary B , Amit Shrivastava B , Taranvir Kaur B , Shabjot Kaur B , Harmandeep Singh Brar B , Ravul Jindal A*DOI: 10.12659/AJCR.938878
Am J Case Rep 2023; 24:e938878
Table 1. Laboratory analysis for the patient from day of admission to day of discharge.
| Parameter | Reference range | Time since hospitalization (Day 0=day of admission) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 3 | Day 5 | Day 8 | Day 9 | Day 10 | Day 12 | Day 13 | Day 19 | Day 20 | Day 22 | Day 29 | Day 32 | ||
| Hemoglobin (g/dl) | 12.0–16.0 | 15.6 | 8.5 | 9.5 | 12.0 | 11.0 | 7.2 | 7.6 | 7.0 | 7.2 | 6.9 | 7.5 | 7.8 | 9.1 |
| Platelet count (thousand/µl) | 150–410 | 22 | 30 | 72 | 150 | 161 | 60 | 70 | 70 | 166 | 167 | 134 | 102 | 141 |
| Leukocytes (thousand/µl) | 4.0–10.0 | 8.2 | 5.3 | 7.2 | 25.7 | 29.9 | 35.5 | 21.8 | 21.0 | 17.9 | 19.5 | 16.2 | 8.1 | 10.4 |
| Activated partial thromboplastin time (sec) | 29.0 | 29.7 | – | – | 24.3 | 31.8 | 24.4 | 26.8 | – | 26.8 | – | – | – | |
| International normalized ratio (INR) | 0.9–1.1 | 1.4 | 1.3 | – | – | 1.3 | 1.9 | 1.2 | 1.2 | – | 1.2 | – | – | – |
| Prothrombin time (sec) | 12.0–14.0 | 18.5 | 16.9 | – | – | 13.4 | 24.7 | 15.7 | 15.4 | – | 15.9 | – | – | – |
| SGOT/aspartate aminotransferase (U/litre) | 20 | 47 | – | – | 42 | – | 114 | – | – | – | 142 | 52 | – | |
| SGPT/alanine aminotransferase (U/litre) | 20 | 63 | – | – | 45 | – | 113 | – | – | – | 295 | 103 | – | |
| Lactate dehydrogenase (U/litre) | 229 | – | – | – | 636 | – | – | – | – | – | – | – | – | |
| Sodium (Na; mmol/L) | 136–145 | 137 | 135 | 137 | 150 | 154 | 159 | 153 | 148 | 138 | 133 | 136 | 135 | 135 |
| Potassium (K; mmol/L) | 3.5–5.1 | 4.2 | 3.7 | 3.0 | 4.4 | 3.6 | 4.5 | 3.7 | 4.3 | 4.1 | 4.0 | 3.5 | 3.4 | 3.4 |
| Chloride (Cl; mmol/L) | 98–107 | 100 | 99 | – | – | 115 | 120 | – | 113 | 102 | 96 | 99 | 97 | 98 |
| Serum creatinine (mg/dl) | 0.7–1.2 | 0.80 | 0.50 | – | – | 0.71 | – | 0.70 | 0.70 | – | – | – | 0.37 | – |