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10 June 2023: Articles

Diagnostic Dilemma in a Case of Lyme Borreliosis Presenting as Severe Anion Gap Metabolic Acidosis: A Case Report

Unusual clinical course, Challenging differential diagnosis, Rare coexistence of disease or pathology

Lindsey A. Wallace A* , Sarah Cullison A , Jacob Bowdon B , Aditya Shah D , Sumera Ahmad A

DOI: 10.12659/AJCR.939196

Am J Case Rep 2023; 24:e939196

Table 2. Cerebrospinal fluid analysis from lumbar puncture.

Patient’s resultReference value/range
ColorClearClear
Protein680–35
Glucose93 mg/dL(60% of plasma glucose)
Total nucleated cells2/mcL0–5/mcL
Erythrocytes1/mcL0/mcL
Neutrophils75%2±4%
Lymphocytes22%60±20%
Monocytes/macrophages3%30±15%
Eosinophils, basophils, other cells0%0%
Blasts00
Encephalitis panel* NegativeNegative
Ehrlichia chaffeensis antibody IgGNegativeNegative
Ehrlichia muris eauclairensisNegativeNegative
Babesia microti, duncani, divergens PCRNegativeNegative
Babesia microti IgG Ab
Powassan virus IgM ELISANegativeNegative
HIV 1/2-antigen and antibody screenNegativeNegative
Syphilis IgG with reflex EIANegativeNegative
RPR screen with reflex to titerNegativeNegative
Urine test for West NileNegativeNegative
* Encephalitis panel tested for the following: K1, , , , , , cytomegalovirus, enterovirus, herpes simplex 1 & 2, human herpesvirus 6, human parechovirus, varicella zoster virus, and . EIA – enzyme immunoassay; HIV – human immunodeficiency virus; RPR – rapid plasma reagin.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923