11 December 2023
: Case report 
An 85-Year-Old Man with Fever, Dyspnea, and Dry Cough Diagnosed with Idiopathic Hypereosinophilic Syndrome, Successfully Treated with High-Dose Corticosteroids
Challenging differential diagnosis, Management of emergency care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Priya Goyal1CDEFG*, Shibba Takkar Chhabra1AF, Rohit Tandon1F, Bhavuk Jaiswal
1BCD, Nikita Sharma1F
DOI: 10.12659/AJCR.941241
Am J Case Rep 2023; 24:e941241
Table 1. Investigation profile.
| Day 0 | Day 4 | Discharge | Follow-up (after 2 weeks) | |
|---|---|---|---|---|
| (gm/dl) | 12.9 | 12.6 | 11.6 | 11.4 |
| (cells/µl) | 20,300 | 18,600 | 9,300 | 7300 |
| N35%, L14%, E45% | N46%, L08%, E40.5% | N76%, L16%, E0% | N74%, L14%, E0% | |
| (cells/µl) | 9000 | 7300 | 0.1 | 0.1 |
| (N-150–450×10 cells/L) | 215 | 198 | 234 | |
| (U/L) | 125 | |||
| (pg/ml) | 213 | |||
| (ng/ml) | 760 | |||
| (ng/ml) | 0.1 | |||
| (<0.9 – Negative) | 0.46 | |||
| (0–20 – Negative) | Negative and 5.0 | |||
| (mm/hr) | 45 | |||
| (IU/L) | 782.6 | |||
| (Normal: 65 U/L to 115 U/L) | 59.2 | |||
| (Normal: 9.3–12.6 sec) | 11.1 s/1.01 | 13.7/1.26 | ||
| Negative | ||||
| Negative | ||||
| (60–79pg/ml – Indeterminate) | 67 pg/ml | |||
| 0.32 index value (Negative) | ||||
| Negative | ||||
| (<0.5ng/ml – Negative) | 0.06 ng/ml | |||
| 119 mg/dl | ||||
| Myeloid predominance with prominence of eosinophils and eosinophilic precursors. | ||||
| B/L Lungs are hyper-inflated. Multiple bilateral centrilobular nodules with surrounding ground-glass haziness and interlobular septal thickening indicative of bronchiolitis. | ||||
| Cardiac chambers are moderately dilated with moderate LV systolic dysfunction. Mild pericardial effusion. Evidence of diffuse sub-endocardial edema noted in left ventricle s/o myocarditis | ||||