02 July 2024
: Case report 
A 68-Year-Old Man with Depression and Acute Renal Failure Due to Rhabdomyolysis Associated with Alcohol Intoxication While Taking Low-Dose Escitalopram: A Case Report
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction
Daniela Cana Ruiu
1ABDEF*, Daniela Teodora Maria1BDEF, Romeo Popa 2BDEF, Sabrina Moraru1ABEF, Elena Georgia Micu3DF, Cristina Vaduva1AD, Naomi Fota1ABD, Dragos George V. Popa4AD, Anca Cojocaru5BD, Daniela Calina5ABDEF
DOI: 10.12659/AJCR.943422
Am J Case Rep 2024; 25:e943422
Table 4. Naranjo Adverse Drug Reaction Probability Scale.
| Question | Yes | No | Do not know | Score |
|---|---|---|---|---|
| 1. Are there previous conclusive reports on this reaction? | +1 | 0 | 0 | 0 |
| 2. Did the adverse event appear after the suspected drug was administered? | +2 | −1 | 0 | +2 |
| 3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | +1 | 0 | 0 | +1 |
| 4. Did the adverse event reappear when the drug was re-administered? | +2 | −1 | 0 | +2 |
| 5. Are there alternative causes (other than the drug) that could on their own have caused the reaction? | −1 | +2 | 0 | −1 |
| 6. Did the reaction reappear when a placebo was given? | −1 | +1 | 0 | +1 |
| 7. Was the drug detected in blood (or other fluids) in concentrations known to be toxic? | +1 | 0 | 0 | 0 |
| 8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | +1 | 0 | 0 | 0 |
| 9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | +1 | 0 | 0 | 0 |
| 10. Was the adverse event confirmed by any objective evidence? | +1 | 0 | 0 | 0 |