Resistant Renovascular Hypertension in Youth: Fibromuscular Dysplasia or Takayasu Arteritis?

21 January 2025 : Case report Poland

Unusual clinical course, Challenging differential diagnosis, Educational Purpose (only if useful for a systematic review or synthesis)

Aneta Michalczewska

^1ABDEF, Jakub Pytlos

^1ABDEF*, Jarosław Żyłkowski

^2ABDE, Remigiusz Krysiak

^3ABDE, Piotr Skrzypczyk

^4ABDEF

DOI: 10.12659/AJCR.945673

Am J Case Rep 2025; 26:e945673

Introduction Case Report Discussion Conclusions References:

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Table 1. Laboratory tests in the presented patient.

Laboratory test (normal values)	Initial examination	Final examination
Age [years]	15 9/12	17 6/12
Creatinine [mg/dL] (0.5–0.9)	0.69	0.77
Urea [mg/dl] (8.6–32.1)	14.9	16.5
Sodium [mmol/L] (130–143)	140	138
Potassium [mmol/L] (3.5–5.1)		4.4
pH [-] (7.350–7.450)		7.41
HCO3- [mmol/L] (19.00–24.00)		25.4
BE [mmol/L] (−3.0-3.0)	3.0	0.8
Plasma renin concentration (upright) [mU/L] (4.4–46.1)		15.91
Plasma aldosterone concentration (upright) [ng/dL] (2.21–35.3)		12.9
Spot urinary protein [mg/dl] (0–15)		Not detected
Urinary albumin-creatinine ratio [mg/g] (<30)		6.8
Total cholesterol [mg/dl] (<170)	141
LDL-cholesterol [mg/dl]	63
HDL cholesterol [mg/dl] (>45)	67
Non-HDL cholesterol [mg/dl]	74
Triglycerides [mg/dl]	53
D-dimer [µg/L FEU] (0–550)	<171
Fibrinogen [g/l] (1.80–3.50)	2.81
C-reactive protein [mg/dl] (<0.5)	0.43
Erythrocyte sedimentation rate [mm/h] (0–12)	4
Complement component 3 [mg/dl] (90.0–180.0)	125.0
Complement component 4 [mg/dl] (10.0–40.0)	26.9
Anti-streptolysin O [IU/ml] (<214)	56.10
IgA [mg/dl] (85.0–194.0)	115.0
IgG [mg/dl] (706.0–1440.0)	1090.0
IgM [mg/dl] (44.0–113.0)	91.50
ANA/DFS70 (anti-DFS 70, anti-M2, anti-RI B, anti-HI, anti-NUC, anti-DNA, anti-PCNA, anti-CB, anti-Jo-1, anti-PM100, anti-Scl, anti-SS B, anti-Ro52, anti-SS A, anti-Sm, anti-RNP/Sm)	Not detected
ANCA (IFA), MPO, PR3	Not detected

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