18 June 2025
: Case report 
Impact of Hypoglossal Nerve Stimulation on Nocturnal Asystole in a Patient with Severe Obstructive Sleep Apnea: A Case Report
Unusual or unexpected effect of treatment
Richard E. Byrne ABCDEF 1*, Candace Miyaki ABCDEF 2DOI: 10.12659/AJCR.947160
Am J Case Rep 2025; 26:e947160
Table 1 Nocturnal asystole (≥5 seconds) compilationThe table demonstrates the frequency of nocturnal asystole (≥5 seconds) events reported by the patient’s implanted loop recorder while using bilevel positive airway pressure (BPAP) and hypoglossal nerve stimulation (HNS).
| Condition | Days of data | Average number of asystole episodes per day (standard deviation) |
|---|---|---|
| On BPAP before HNS | 60 | 0.00 (0.000) |
| Off BPAP on HNS | 24 | 0.79 (0.833)* |
| Resumed BPAP off HNS | 18 | 0.00 (0.000) |
| * Statistically significant difference ( | ||