09 July 2025
: Case report 
Selective IgA Deficiency Complicated with Pernicious Anemia Diagnosed After Febrile Non-Hemolytic Transfusion Reaction
Rare disease
Yuta Yoshino
ABCDEF 1*, Natsumi Kosugi BCDF 1
DOI: 10.12659/AJCR.947678
Am J Case Rep 2025; 26:e947678
Table 2 Additional biochemical test.
| Variable | Result | Normal values |
|---|---|---|
| Vitamin B12 (pg/mL) | 102 | 233–914 |
| Folic acid (ng/mL) | 11.8 | 3.6–12.9 |
| Haptoglobin (mg/dL) | 2 | 19–170 |
| Interleukin-2 receptor (U/mL) | 470 | 122–496 |
| Antinuclear antibody | Negative | Negative |
| Anticardiolipin-IgG antibody (U/mL) | 2.6 | 0.0–20.0 |
| Anti-parietal cell antibody | Negative | Negative |
| Anti-intrinsic factor antibody | Negative | Negative |
| Anti-helicobacter pylori-IgG antibody (U/mL) | <3.0 | 0.0–9.9 |
| Complement C3 (mg/dL) | 81 | 80–140 |
| Complement C4 (mg/dL) | 26.3 | 11–34 |
| ADAMTS13 activity (IU/mL) | 0.40 | >0.10 |
| Immunoglobulin G (mg/dL) | 1303 | 820–1740 |
| Immunoglobulin A (mg/dL) | <3.0 | 90–400 |
| Immunoglobulin M (mg/dL) | 44 | 31–200 |
| ADAMTS13 – a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13. | ||