09 July 2025
: Case report 
Selective IgA Deficiency Complicated with Pernicious Anemia Diagnosed After Febrile Non-Hemolytic Transfusion Reaction
Rare disease
Yuta Yoshino
ABCDEF 1*, Natsumi Kosugi BCDF 1
DOI: 10.12659/AJCR.947678
Am J Case Rep 2025; 26:e947678
Table 3 Timeline with recovery from cytopenia and key laboratory findings.
| Variable | Normal range | Day 1 | Day 3 | Day 4 | Day 6 | Day 8 | Day 10 | Day15 | Day 28 |
|---|---|---|---|---|---|---|---|---|---|
| Erythrocyte (10/mm) | 4.38–5.77 | 1.33 | 1.43 | 1.54 | 1.79 | 2.18 | 2.40 | 2.73 | 3.67 |
| Hemoglobin (g/dL) | 13.6–18.3 | 5.0 | 5.0 | 5.4 | 6.1 | 6.8 | 7.4 | 7.8 | 10.2 |
| Hematocrit (%) | 40.4–51.9 | 15.1 | 15.4 | 17.3 | 20.5 | 23.9 | 25.0 | 27.4 | |
| MCV (fL) | 83–101 | 113.5 | 107.7 | 112.3 | 114.5 | 109.6 | 104.2 | 100.4 | |
| Reticulocyte (10/mm) | 5.0–15.0 | 3.21 | 4.30 | 17.3 | 43.9 | 31.5 | 12.3 | 5.5 | 2.4 |
| Platelets (10/mm) | 14.0–37.9 | 5.8 | 4.4 | 4.6 | 5.2 | 29.4 | 63.7 | 84.2 | 38.5 |
| LD (U/L) | 120–245 | 3220 | 2160 | 1890 | 1323 | 1135 | 772 | 393 | 175 |
| Total bilirubin (mg/dL) | 0.3–1.2 | 2.2 | 2.0 | 1.7 | 1.5 | 1.5 | 1.3 | 0.6 | |
| MCV – mean corpuscular volume; LD – lactate dehydrogenase. | |||||||||