Sleeve Resection of the Right Upper Lobe for Tracheobronchial Metastasis of Hepatocellular Carcinoma With Superior Vena Cava Involvement: A Case Report and Literature Review

12 May 2026 : Case report China

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease

Peng Cao^{ABEF 1,2}, Yulin Wang^{BCDF 1,3}, Qing Wang^{ABCD 1}, Wei Cai^{ABE 1,4}, Rui Zhang

^{DG 2}, Zhigang Li^{ABCDG 1*}, Junfeng Geng^{ABCDEFG 1}

DOI: 10.12659/AJCR.952125

Am J Case Rep 2026; 27:e952125

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Table 1 Characteristics of endobronchial metastases from hepatocellular carcinoma: a case series analysis from 1988 to 2025.

Gender	Age	Presentation/symptoms	Bronchus location	Treatment	Author	Year
F	66	Pneumonia	Right upper lobe	Chemotherapy	Camps []⁷	1988
M	61	Cough, hemoptysis	Right main bronchus	NA	Marayama []⁸	1992
NA	NA	NA	NA	NA	Salud []⁹	1996
F	61	Cough, hemoptysis	Right upper lobe	Lobectomy	Lee []⁴	2003
M	80	Hemoptysis	Left lower lobe	Radiotherapy	Kido []¹⁰	2005
M	65	Hemoptysis	Right bronchus intermedius	Pneumonectomy	Purandare []⁵	2009
F	71	Dyspnea, respiratory failure	Bilateral	Bronchial Stent	Uchida []¹¹	2010
F	20	Dyspnea, chest pain	Right upper lobe	Sorafenib + chemotherapy	Szumera []²	2013
M	51	Cough	Left lower lobe	NA	Dong []¹²	2014
F	63	Dyspnea, cough	Right upper lobe	Supportive care	ElBadrawy []¹³	2018
M	62	Cough, hemoptysis	Bilateral	Bronchoscopy + pembrolizumab	Cheung []³	2019
M	72	Hemoptysis	Right upper lobe	NA	Cai []¹⁴	2020
M	80	NA	Right upper lobe	Sorafenib	Zhang []¹⁵	2022
M	62	Hemoptysis, weight loss	Bilateral lower lobes	Lenvatinib	Koay L []¹⁶	2023
M	74	Hemoptysis, dry cough	Right B3b and B10 bronchi	Lenvatinib monotherapy	Takei []¹⁷	2023
M	62	Hemoptysis, coughing	Right superior lobar bronchus	Sleeve resection of the right upper lobe	Current report	2025

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