03 September 2026
: Case report 
When Grief Strains the Heart: A Case of Reverse Takotsubo Cardiomyopathy Triggered by Mourning and Respiratory Failure
Rare disease
Peter Cwalina ABCDEF 1*, Ibrahim Rahmatullah DE 2, Ayesha Samad ABCDEF 2, Adam S. Budzikowski CDE 3DOI: 10.12659/AJCR.952896
Am J Case Rep 2026; 27:e952896
Table 3 Application of InterTAK Diagnostic Score.
| InterTAK Diagnostic Score variable | Points | Present in this case |
|---|---|---|
| Female sex | 25 | Yes |
| Emotional trigger | 24 | No – Chronic rather than acute |
| Physical trigger | 13 | Yes – Acute respiratory failure |
| Absence of ST-segment depression | 12 | Yes |
| Psychiatric disorders | 11 | No |
| Neurologic disorders | 9 | No |
| QTc prolongation | 6 | No |