Cone-Beam Computed Tomography Imaging of Primary Non-Hodgkin Lymphoma of the Jaws: A 6-Case Series

09 September 2026 : Case report Greece

Challenging differential diagnosis, Rare disease

Emmanouil Chatzipetros

^{ABCDEFG 1*}, Konstantina-Eleni Alexiou

^{BDEG 1}, Kostas Tsiklakis^{ABEG 1}, Christos Angelopoulos^{AFG 1}

DOI: 10.12659/AJCR.954314

Am J Case Rep 2026; 27:e954314

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Table 1 Clinical, radiological, and demographic characteristics of 6 patients with non-Hodgkin lymphoma (NHL) involving the jaws.

Features	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
Sex	Female	Male	Male	Female	Female	Male
Age	45	66	40	79	44	35
Chief concern	Paresthesia	Paresthesia	ParesthesiaTooth mobilityFacial swelling	Tooth mobility	Paresthesia	ParesthesiaTooth mobilityFacial swelling
Medical history	Unremarkable	Unremarkable	Unremarkable	Unremarkable	Unremarkable	HIV-positive (newly diagnosed)
Lesion location	Left posterior mandible	Left posterior mandible	Right posterior mandible	Right posterior maxilla	Left posterior mandible	Right posterior mandible
Number of lesions	Single	Two in the same region	Single	Single	Single	Single
Internal architecture	Osteolytic	Osteolytic	Osteolytic	Osteolytic	Osteolytic	Osteolytic
Lesion extent	Limited	Limited	Extensive	Extensive	Moderate	Extensive
Lesion borders	Ill-definedMoth-eaten	Ill-definedMoth-eaten	Ill-definedMoth-eaten	Ill-definedMoth-eaten	Ill-definedMoth-eaten	Ill-definedMoth-eaten
Effects on bony cortex	ErosionInfiltration	Infiltration	Destruction	Destruction	Destruction	Destruction
Effects on adjacent teeth	Edentulous area	Edentulous area	Floating teethSpiked-tooth effect	Floating teethSpiked-tooth effect	Spiked-tooth effect	Floating teethSpiked-tooth effect
Periosteal reaction	Absent	Absent	Absent	Absent	Absent	Absent
Involvement of mandibular canal	Present	Present	Present	Absent	Present	Present
Involvement of maxillary sinus and/or nasal cavity	Absent	Absent	Absent	Present	Absent	Absent
Pathological fractures	Absent	Absent	Absent	Absent	Absent	Present

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