29 January 2008
Association of increased QTc dispersion and right ventricular hypertrophy
Mustafa TuncerABE, Yilmaz GunesCDEF, Unal GuntekinBF, Sukru AslanBC, Hasan Ali GumrukcuogluB, Beyhan EryonucuA, Cengiz ErmisEMed Sci Monit 2008; 14(2): CR102-105 :: ID: 734759
Abstract
Background
There have been reports demonstrating an association between increased QT dispersion and ventricular arrhythmia in a variety of pathological cardiac conditions, including left ventricular hypertrophy. However, there are limited data about an association of right ventricular hypertrophy (RVH) and corrected QT (QTc) dispersion.
Material and Method
Eighty-five persons who emigrated from a high-altitude region (2800-4200 m) of Afghanistan to Van, Turkey, (altitude: 1700-1800 m) 25 years ago were referred to our hospital for transthoracic examination between April 2003 and May 2007. RVH was detected in 37 of the persons, 12 of whom were not included in the study due to coexisting systemic hypertension, COPD, or pulmonary hypertension. Twenty-five individuals of the same population with normal echocardiographic findings were enrolled as the control group. Symptoms that may be consequent to arrhythmia (such as palpitation, dizziness, and syncope) were not reported by the study population. Twelve-lead electrography was performed to measure the heart rate, QTc intervals, and QTc dispersion values.
Results
The age and gender of both the patient and control groups were similar. There was no significant difference between patients and controls with respect to QTmax, QTmin, and heart rate. However, mean QTc dispersion values were significantly increased in patients with RVH compared with the control group (59.0+/-14.7 vs. 35.9+/-11.4 ms, p<0.001).
Conclusions
Right ventricular hypertrophy is associated with an increase in QTc dispersion.
Keywords: Hypertrophy, Right Ventricular - physiopathology, Heart Rate, Emigration and Immigration, Electrocardiography, Turkey, Case-Control Studies, Altitude, Afghanistan - ethnology
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
12 Mar 2024 : Review article
Optimizing Behçet Uveitis Management: A Review of Personalized Immunosuppressive StrategiesMed Sci Monit In Press; DOI: 10.12659/MSM.943240
12 Mar 2024 : Clinical Research
Metabolomic Alterations in Methotrexate Treatment of Moderate-to-Severe PsoriasisMed Sci Monit In Press; DOI: 10.12659/MSM.943360
14 Mar 2024 : Clinical Research
Renal Dysfunction Increases Risk of Adverse Cardiovascular Events in 5-Year Follow-Up Study of Intermediate...Med Sci Monit In Press; DOI: 10.12659/MSM.943956
15 Mar 2024 : Clinical Research
Impact of One-Lung Ventilation on Oxygenation and Ventilation Time in Thoracoscopic Heart Surgery: A Compar...Med Sci Monit In Press; DOI: 10.12659/MSM.943089
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952