20 April 2019 : Clinical Research
Femoral Artery Sclerosis Evaluation by Tissue Doppler in Patients with Hypertension
Xianghong Lei1ABC*, Juan Liu1CDEDOI: 10.12659/MSM.913271
Med Sci Monit 2019; 25:2917-2922
Abstract
BACKGROUND: The aim of this study was to evaluate the early femoral sclerosis in hypertensive patients by using tissue Doppler imaging (TDI).
MATERIAL AND METHODS: One hundred patients with hypertension were recruited and divided into group A (femoral artery intima-media thicknesses (IMT) ≥1.0 mm) and group B (femoral artery IMT <1.0 mm) with 50 cases in each group based on the femoral IMT. In addition, 50 healthy controls were also included in this study. Femoral wall structure and femoral artery IMT were examined by using high frequency ultrasound. Pulsed wave (PW)-TDI was used to obtain the motion curve of the posterior wall of the femoral artery. First (T1) and second (T2) peak duration were also obtained.
RESULTS: The IMT of group A, group B, and the healthy control group were 1.17±0.12 mm, 0.74±0.11 mm, and 0.71±0.09 mm respectively with significant statistical difference (P<0.05). The first peak duration (T1) of the 3 groups (group A, group B, and healthy control group) were 135.6±16.6 ms, 134.5±18.5 ms, and 129.8±12.4 ms, respectively without statistical difference (F=1.868 P=0.158). The second peak duration (T2) of group A, group B, and the healthy control group were 234.7±39.8 ms, 209.3±34.9 ms, and 169.8±19.5 ms respectively with statistically significant difference (F=50.411 P=0.000). The diagnostic sensitivity, specificity area under the curve (AUC) and cutoff value for early arteriosclerosis diagnosis of femoral artery by T1 was 56.0% (95% CI: 41.3–70.0%), 66.0% (95% CI: 51.2–78.8%), AUC=0.54 (95% CI: 0.42–0.66) and 130.5 ms respectively. And it was 64.0% (95% CI: 49.2–77.1%), 62.0% (95% CI: 47.2–75.4%), AUC=0.69 (95% CI: 0.59–0.80) and 214.5 ms respectively for T2.
CONCLUSIONS: TDI can be used as an effective index for early femoral artery sclerosis before femoral artery IMT changes.
Keywords: Amyotrophic Lateral Sclerosis, Echocardiography, Doppler, Femoral Artery, Hypertension, Arteriosclerosis, Tunica Intima, Ultrasonography, Ultrasonography, Doppler
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
11 Mar 2024 : Clinical Research
Comparison of Effects of Sugammadex and Neostigmine on Postoperative Neuromuscular Blockade Recovery in Pat...Med Sci Monit In Press; DOI: 10.12659/MSM.942773
12 Mar 2024 : Clinical Research
Comparing Neuromuscular Blockade Measurement Between Upper Arm (TOF Cuff®) and Eyelid (TOF Scan®) Using Miv...Med Sci Monit In Press; DOI: 10.12659/MSM.943630
11 Mar 2024 : Clinical Research
Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective AdditiveMed Sci Monit In Press; DOI: 10.12659/MSM.942946
12 Mar 2024 : Database Analysis
Risk Factors of Age-Related Macular Degeneration in a Population-Based Study: Results from SHIP-TREND-1 (St...Med Sci Monit In Press; DOI: 10.12659/MSM.943140
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952