01 August 2019
: Case report
Basic Calcium Phosphate Crystal Periarthritis Involving the Distal Interphalangeal Joints in a Patient with Systemic Lupus Erythematosus
Rare coexistence of disease or pathology
Linett Martirossian1EF*, Andreea M. Bujor1DEF, Eugene Kissin1DEFDOI: 10.12659/AJCR.916118
Am J Case Rep 2019; 20:1132-1137
Abstract
BACKGROUND: Increased serum levels of basic calcium phosphate (BCP) and calcium pyrophosphate (CPP) are found in patients on dialysis, following trauma, and are associated with connective tissue diseases (CTDs), including dermatomyositis, scleroderma, and systemic lupus erythematosus (SLE). The shoulder is the joint most commonly associated with BCP crystal periarthritis. A report is presented of a case of BCP crystal periarthritis involving the distal interphalangeal (DIP) joints in a patient with SLE.
CASE REPORT: A 34-year-old woman with SLE presented with destructive arthritis of the DIP joints that developed during a two-year period, despite immunosuppressive therapy. Aspiration of synovial fluid from a DIP joint showed a lack of inflammatory cells, but the fluid was positive for the presence of crystals on alizarin red S histochemical staining.
CONCLUSIONS: A case of BCP crystal periarthritis is reported in a patient with SLE with chronic joint symptoms that were unresponsive to immunosuppressive therapy. This case has shown that chronic joint symptoms that are unresponsive to immunosuppressive therapy may be due to causes other than connective tissue disease (CTD) and that imaging studies and diagnostic workup that includes synovial fluid examination may support the diagnosis of BCP crystal periarthritis.
Keywords: Arthritis, Calcium Phosphates, lupus nephritis, Adult, Anthraquinones, Crystal Arthropathies, Finger Joint, Lupus Erythematosus, Systemic, periarthritis
SARS-CoV-2/COVID-19
04 July 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.934468
29 June 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936896
16 June 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936498
13 June 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936889
In Press
04 Jul 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936836
04 Jul 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.934468
04 Jul 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936448
01 Jul 2022 : Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936536
Most Viewed Current Articles
23 Feb 2022 : Case report
DOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250
17 Feb 2022 : Case report
DOI :10.12659/AJCR.934399
Am J Case Rep 2022; 23:e934399
06 Dec 2021 : Case report
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
09 Feb 2022 : Case report
DOI :10.12659/AJCR.934744
Am J Case Rep 2022; 23:e934744