Rare disease

08 Nov 2025 : Case report
Novel Airway Challenges in DEGCAGS Syndrome: Managing Infant Laryngeal Hamartomas
Hongfang Duan, Chen Chen, Guo Xu, Tingting Yao, Xiangyu Ma, Delun Zhang
DOI: 10.12659/AJCR.948733
Am J Case Rep 2025; 26:e948733
818 1,386 0

08 Nov 2025 : Case report
Novel Airway Challenges in DEGCAGS Syndrome: Managing Infant Laryngeal Hamartomas
Hongfang Duan, Chen Chen, Guo Xu, Tingting Yao, Xiangyu Ma, Delun Zhang
DOI: 10.12659/AJCR.948733
Am J Case Rep 2025; 26:e948733
818 1386 0

27 Oct 2025 : Case report
Parasitic Gallbladder Infection: Case Study of Biliary Clonorchiasis in a Non-Endemic Region
Hamzeh Al-Balas, Mahmoud Al-Balas
, Mohammed Alorjani
, Mohammad Bani Hani, Sara A. Abusini
, Raneem El-Faouri
DOI: 10.12659/AJCR.949206
Am J Case Rep 2025; 26:e949206
657 2,598 0

27 Oct 2025 : Case report
Parasitic Gallbladder Infection: Case Study of Biliary Clonorchiasis in a Non-Endemic Region
Hamzeh Al-Balas, Mahmoud Al-Balas
, Mohammed Alorjani
, Mohammad Bani Hani, Sara A. Abusini
, Raneem El-Faouri
DOI: 10.12659/AJCR.949206
Am J Case Rep 2025; 26:e949206
657 2598 0

25 Oct 2025 : Case report
Intraosseous Cellular Schwannoma in the Infraorbital Region: A Rare Case
Edmundo Luis Rodrigues Pereira
, Rebeca Viera Costa, Jeovanna Brito de Moraes
, Alessandra Arnaud Moreira, Thayna Silva do Carmo Tavares
, Fabricio Passador-Santos
, Lucas Rodrigues Pinheiro
, Sérgio de Melo Alves Júnior
, João de Jesus Viana Pinheiro
DOI: 10.12659/AJCR.947024
Am J Case Rep 2025; 26:e947024
617 1,461 0

25 Oct 2025 : Case report
Intraosseous Cellular Schwannoma in the Infraorbital Region: A Rare Case
Edmundo Luis Rodrigues Pereira
, Rebeca Viera Costa, Jeovanna Brito de Moraes
, Alessandra Arnaud Moreira, Thayna Silva do Carmo Tavares
, Fabricio Passador-Santos
, Lucas Rodrigues Pinheiro
, Sérgio de Melo Alves Júnior
, João de Jesus Viana Pinheiro
DOI: 10.12659/AJCR.947024
Am J Case Rep 2025; 26:e947024
617 1461 0

29 Sep 2025 : Case report
Complex Ocular Adverse Events Following Oxaliplatin Treatment: A Case Report
Chao-Yang Zhao, Chang-Sheng Liao, Zi-You Yuan, Chen-Yue Zhao, Shao-Feng Hao
, Hui-Lin Li
DOI: 10.12659/AJCR.949346
Am J Case Rep 2025; 26:e949346
453 929 0

29 Sep 2025 : Case report
Complex Ocular Adverse Events Following Oxaliplatin Treatment: A Case Report
Chao-Yang Zhao, Chang-Sheng Liao, Zi-You Yuan, Chen-Yue Zhao, Shao-Feng Hao
, Hui-Lin Li
DOI: 10.12659/AJCR.949346
Am J Case Rep 2025; 26:e949346
453 929 0

29 Oct 2025 : Case report
Gastric Adenocarcinoma Resembling Submucosal Tumor: A Case Report
Hongli Liu, Chao Deng, Rui Song, Juan Li, Song He, Zhihang Zhou, Suhua Wu, Hongdan Cao, Lin Lv
DOI: 10.12659/AJCR.949785
Am J Case Rep 2025; 26:e949785
711 3,268 0

29 Oct 2025 : Case report
Gastric Adenocarcinoma Resembling Submucosal Tumor: A Case Report
Hongli Liu, Chao Deng, Rui Song, Juan Li, Song He, Zhihang Zhou, Suhua Wu, Hongdan Cao, Lin Lv
DOI: 10.12659/AJCR.949785
Am J Case Rep 2025; 26:e949785
711 3268 0

26 Oct 2025 : Case report
Diagnostic Challenges in Cerebral Schistosomiasis: A Case of Schistosoma japonicum Misinterpretation
Qian Lu, Shitong Gao, Gang Li, Xuesen He, Panjue Chen, Changqing Tu
DOI: 10.12659/AJCR.948044
Am J Case Rep 2025; 26:e948044
632 2,456 0

26 Oct 2025 : Case report
Diagnostic Challenges in Cerebral Schistosomiasis: A Case of Schistosoma japonicum Misinterpretation
Qian Lu, Shitong Gao, Gang Li, Xuesen He, Panjue Chen, Changqing Tu
DOI: 10.12659/AJCR.948044
Am J Case Rep 2025; 26:e948044
632 2456 0

26 Oct 2025 : Case report
Oral Tamoxifen and Abemaciclib in Postoperative Therapy for Male Breast Cancer: A Case Report
Kei Ishii
, Masae Torii, Hiroshi Yoshibayashi, Yoshiaki Matsumoto
, Yasuo Matsutani
DOI: 10.12659/AJCR.949005
Am J Case Rep 2025; 26:e949005
618 2,195 0

26 Oct 2025 : Case report
Oral Tamoxifen and Abemaciclib in Postoperative Therapy for Male Breast Cancer: A Case Report
Kei Ishii
, Masae Torii, Hiroshi Yoshibayashi, Yoshiaki Matsumoto
, Yasuo Matsutani
DOI: 10.12659/AJCR.949005
Am J Case Rep 2025; 26:e949005
618 2195 0

24 Oct 2025 : Case report
Management and Surgical Dressing Protocol for Cutaneous Mucormycosis After a Blast Injury: A Case Report
Abdulaziz M. Tawffeq, Talal A. Almutairi
, Rema F. Alrashed
, Ayed I. Almutairi, Nagoud M. Ali
DOI: 10.12659/AJCR.949392
Am J Case Rep 2025; 26:e949392
529 2,453 0

24 Oct 2025 : Case report
Management and Surgical Dressing Protocol for Cutaneous Mucormycosis After a Blast Injury: A Case Report
Abdulaziz M. Tawffeq, Talal A. Almutairi
, Rema F. Alrashed
, Ayed I. Almutairi, Nagoud M. Ali
DOI: 10.12659/AJCR.949392
Am J Case Rep 2025; 26:e949392
529 2453 0

23 Oct 2025 : Case report
Isolated Pulmonary Regurgitation without Right Heart Remodeling or Pulmonary Hypertension
Robert Doyle, Mark Wilkinson
DOI: 10.12659/AJCR.949786
Am J Case Rep 2025; 26:e949786
541 2,388 0

23 Oct 2025 : Case report
Isolated Pulmonary Regurgitation without Right Heart Remodeling or Pulmonary Hypertension
Robert Doyle, Mark Wilkinson
DOI: 10.12659/AJCR.949786
Am J Case Rep 2025; 26:e949786
541 2388 0

23 Sep 2025 : Case report
Acupotomy to Treat Inversion of the Second Toe Combined with Eversion of the First Metatarsophalangeal Toe: A Case Report
Zehao Hu, Hao Qin, Qiuxuan Huang, Zhanxin Li
DOI: 10.12659/AJCR.949599
Am J Case Rep 2025; 26:e949599
361 1,110 0

23 Sep 2025 : Case report
Acupotomy to Treat Inversion of the Second Toe Combined with Eversion of the First Metatarsophalangeal Toe: A Case Report
Zehao Hu, Hao Qin, Qiuxuan Huang, Zhanxin Li
DOI: 10.12659/AJCR.949599
Am J Case Rep 2025; 26:e949599
361 1110 0

21 Oct 2025 : Case report
High-Grade Angiosarcoma Transformation in Schwannoma and SMARCB1 Mutation: A Case Report
Lydia Mbatidde, Rohit Sharma, Michael J. Michalske, Jaswinder Chalia, Adedayo A. Onitilo
DOI: 10.12659/AJCR.947742
Am J Case Rep 2025; 26:e947742
502 1,424 0

21 Oct 2025 : Case report
High-Grade Angiosarcoma Transformation in Schwannoma and SMARCB1 Mutation: A Case Report
Lydia Mbatidde, Rohit Sharma, Michael J. Michalske, Jaswinder Chalia, Adedayo A. Onitilo
DOI: 10.12659/AJCR.947742
Am J Case Rep 2025; 26:e947742
502 1424 0

20 Oct 2025 : Case report
Severe Chemoradiotherapy Toxicity in a Pediatric Patient with Leigh Syndrome and Grade IV Isocitrate Dehydrogenase-Mutant Astrocytoma: A Case Report
Madison T. Granberry, Tyler Severance
, Gregory Biedermann
, Carolyn Quinsey, Dana G. Mazuru, Alicia Bach
DOI: 10.12659/AJCR.949191
Am J Case Rep 2025; 26:e949191
511 1,240 0

20 Oct 2025 : Case report
Severe Chemoradiotherapy Toxicity in a Pediatric Patient with Leigh Syndrome and Grade IV Isocitrate Dehydrogenase-Mutant Astrocytoma: A Case Report
Madison T. Granberry, Tyler Severance
, Gregory Biedermann
, Carolyn Quinsey, Dana G. Mazuru, Alicia Bach
DOI: 10.12659/AJCR.949191
Am J Case Rep 2025; 26:e949191
511 1240 0

23 Oct 2025 : Case report
Left Ventricle Libman-Sacks Endocarditis Secondary to Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report
Zi-hao Yang, Wen-qing Gong, Ying Liu, Min-juan Zheng
DOI: 10.12659/AJCR.949826
Am J Case Rep 2025; 26:e949826
685 1,630 0

23 Oct 2025 : Case report
Left Ventricle Libman-Sacks Endocarditis Secondary to Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report
Zi-hao Yang, Wen-qing Gong, Ying Liu, Min-juan Zheng
DOI: 10.12659/AJCR.949826
Am J Case Rep 2025; 26:e949826
685 1630 0

21 Oct 2025 : Case report
Methimazole-Induced Antithyroid Arthritis Syndrome in Graves' Disease Management: A Case Report
DOI: 10.12659/AJCR.949509
Am J Case Rep 2025; 26:e949509
822 4,509 0

21 Oct 2025 : Case report
Methimazole-Induced Antithyroid Arthritis Syndrome in Graves' Disease Management: A Case Report
DOI: 10.12659/AJCR.949509
Am J Case Rep 2025; 26:e949509
822 4509 0

16 Oct 2025 : Case report
A Hybrid Approach in Treating a Mycotic Aneurism Caused by MRSA: A Case Report
Camilo Andres Calderon-Miranda
, Luz Clemencia Zárate-Correa
, María Juliana Reyes-Cardona
, Pastor Olaya
, Jairo Sanchez-Blanco
, Jorge Alexander Zambrano-Franco
, Juan Pablo Carbonell
, Enrique Carlos García-Pretelt
, Carlos Enrique Vesga-Reyes
DOI: 10.12659/AJCR.950007
Am J Case Rep 2025; 26:e950007
536 2,464 0

16 Oct 2025 : Case report
A Hybrid Approach in Treating a Mycotic Aneurism Caused by MRSA: A Case Report
Camilo Andres Calderon-Miranda
, Luz Clemencia Zárate-Correa
, María Juliana Reyes-Cardona
, Pastor Olaya
, Jairo Sanchez-Blanco
, Jorge Alexander Zambrano-Franco
, Juan Pablo Carbonell
, Enrique Carlos García-Pretelt
, Carlos Enrique Vesga-Reyes
DOI: 10.12659/AJCR.950007
Am J Case Rep 2025; 26:e950007
536 2464 0

19 Oct 2025 : Case report
Retroperitoneal Necrotizing Fasciitis Mimicking Fournier Gangrene: A Rare and Severe Diagnostic Entity
Xun Wang, Yang Li, Jing Wang
DOI: 10.12659/AJCR.949312
Am J Case Rep 2025; 26:e949312
435 2,003 0

19 Oct 2025 : Case report
Retroperitoneal Necrotizing Fasciitis Mimicking Fournier Gangrene: A Rare and Severe Diagnostic Entity
Xun Wang, Yang Li, Jing Wang
DOI: 10.12659/AJCR.949312
Am J Case Rep 2025; 26:e949312
435 2003 0

09 Oct 2025 : Case report
Novel Variant of RARB Gene in Familial Isolated Ocular Coloboma: A Case Report
Grace Z. Armstrong, Kathleen K. Ho, Tyler J. Knight, Erin E. Conboy
DOI: 10.12659/AJCR.949311
Am J Case Rep 2025; 26:e949311
419 1,531 0

09 Oct 2025 : Case report
Novel Variant of RARB Gene in Familial Isolated Ocular Coloboma: A Case Report
Grace Z. Armstrong, Kathleen K. Ho, Tyler J. Knight, Erin E. Conboy
DOI: 10.12659/AJCR.949311
Am J Case Rep 2025; 26:e949311
419 1531 0

16 Oct 2025 : Case report
Renal Cell Carcinoma with Fibromyomatous Stroma: A Case Report
Eman Mostafa Keshk, Ammara Kashif, Abdullah Sulaiman Alsulaiman, Nawal Ahmed Abdullah, Saud Omar Alafghani, Hisham Saeed Jamaan Alzahrani, Ensherah Mohammed Alghamdi, Rawan Khader Alhuthali, Khalid Ahmed Alasiri, Rasha Fayez Alharthi, Rakan Fayez Alharthi, Hussian R. Barnawi, Wafa Mutlag Alotaibi
DOI: 10.12659/AJCR.948666
Am J Case Rep 2025; 26:e948666
462 2,127 0

16 Oct 2025 : Case report
Renal Cell Carcinoma with Fibromyomatous Stroma: A Case Report
Eman Mostafa Keshk, Ammara Kashif, Abdullah Sulaiman Alsulaiman, Nawal Ahmed Abdullah, Saud Omar Alafghani, Hisham Saeed Jamaan Alzahrani, Ensherah Mohammed Alghamdi, Rawan Khader Alhuthali, Khalid Ahmed Alasiri, Rasha Fayez Alharthi, Rakan Fayez Alharthi, Hussian R. Barnawi, Wafa Mutlag Alotaibi
DOI: 10.12659/AJCR.948666
Am J Case Rep 2025; 26:e948666
462 2127 0

15 Oct 2025 : Case report
Uncommon Localization of Tenosynovial Giant Cell Tumor in the Coracoclavicular Ligament: Diagnostic Challenges
Zeming Li, Hao Feng, Lingyun Chen, Jun Yao, Hongtao Wang
DOI: 10.12659/AJCR.949269
Am J Case Rep 2025; 26:e949269
505 1,405 0

15 Oct 2025 : Case report
Uncommon Localization of Tenosynovial Giant Cell Tumor in the Coracoclavicular Ligament: Diagnostic Challenges
Zeming Li, Hao Feng, Lingyun Chen, Jun Yao, Hongtao Wang
DOI: 10.12659/AJCR.949269
Am J Case Rep 2025; 26:e949269
505 1405 0

12 Oct 2025 : Case report
Laparoscopic Repair of Diaphragmatic Pericardial Hernia Following Blunt Trauma: A Case Report
Mohammad Al Yaseen, Moamena El Matbouly
, Ahmed Suliman, Ahmed Zuhair Al Bahrani
DOI: 10.12659/AJCR.948775
Am J Case Rep 2025; 26:e948775
428 1,407 0

12 Oct 2025 : Case report
Laparoscopic Repair of Diaphragmatic Pericardial Hernia Following Blunt Trauma: A Case Report
Mohammad Al Yaseen, Moamena El Matbouly
, Ahmed Suliman, Ahmed Zuhair Al Bahrani
DOI: 10.12659/AJCR.948775
Am J Case Rep 2025; 26:e948775
428 1407 0

05 Oct 2025 : Case report
Enhancing Detection and Management of Spontaneous Bilateral Ectopic Pregnancies: Insights From a Rare Case
Haneen AlJalodi, Farah AlMughrbi, Kat Pavlidi, Penny Robshaw
DOI: 10.12659/AJCR.949468
Am J Case Rep 2025; 26:e949468
391 1,470 0

05 Oct 2025 : Case report
Enhancing Detection and Management of Spontaneous Bilateral Ectopic Pregnancies: Insights From a Rare Case
Haneen AlJalodi, Farah AlMughrbi, Kat Pavlidi, Penny Robshaw
DOI: 10.12659/AJCR.949468
Am J Case Rep 2025; 26:e949468
391 1470 0

03 Sep 2025 : Case report
Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review
Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida
DOI: 10.12659/AJCR.947151
Am J Case Rep 2025; 26:e947151
548 2,123 0

03 Sep 2025 : Case report
Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review
Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida
DOI: 10.12659/AJCR.947151
Am J Case Rep 2025; 26:e947151
548 2123 0

05 Oct 2025 : Case report
Cardiotoxicity Secondary to Accidental Tilmicosin (Micotil®300) Ingestion in a Young Shepherd: A Case Report
Zein B. Sheikh, Bayan S. Alalawi
, Fadyah M. Alradaddi, Ahlam Y. Elbadri
DOI: 10.12659/AJCR.948094
Am J Case Rep 2025; 26:e948094
433 1,888 0

05 Oct 2025 : Case report
Cardiotoxicity Secondary to Accidental Tilmicosin (Micotil®300) Ingestion in a Young Shepherd: A Case Report
Zein B. Sheikh, Bayan S. Alalawi
, Fadyah M. Alradaddi, Ahlam Y. Elbadri
DOI: 10.12659/AJCR.948094
Am J Case Rep 2025; 26:e948094
433 1888 0

04 Oct 2025 : Case report
Novel Use of Robotic Surgery in a Rare Case of Canal of Nuck Cyst: A Case Report and Literature Review
Winnie Long, Jamie Han, Luca Milone
DOI: 10.12659/AJCR.949239
Am J Case Rep 2025; 26:e949239
340 1,478 0

04 Oct 2025 : Case report
Novel Use of Robotic Surgery in a Rare Case of Canal of Nuck Cyst: A Case Report and Literature Review
Winnie Long, Jamie Han, Luca Milone
DOI: 10.12659/AJCR.949239
Am J Case Rep 2025; 26:e949239
340 1478 0

04 Oct 2025 : Case report
Perforated Meckel Diverticulum Caused by Vegetal Food Entrapment: A Rare Case Report and Literature Review
Odile Sorg, Xenofon Papazarkadas
, Michaël Racine
, Christian Toso
, Stefan Mönig
DOI: 10.12659/AJCR.948592
Am J Case Rep 2025; 26:e948592
418 1,417 0

04 Oct 2025 : Case report
Perforated Meckel Diverticulum Caused by Vegetal Food Entrapment: A Rare Case Report and Literature Review
Odile Sorg, Xenofon Papazarkadas
, Michaël Racine
, Christian Toso
, Stefan Mönig
DOI: 10.12659/AJCR.948592
Am J Case Rep 2025; 26:e948592
418 1417 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952819
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952834
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.953320
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.952980
Most Viewed Current Articles
07 Dec 2021 : Case report
22,766,348
DOI :10.12659/AJCR.934347
Am J Case Rep 2021; 22:e934347
06 Dec 2021 : Case report
177,710
DOI :10.12659/AJCR.934406
Am J Case Rep 2021; 22:e934406
21 Jun 2024 : Case report
121,485
DOI :10.12659/AJCR.944371
Am J Case Rep 2024; 25:e944371
07 Mar 2024 : Case report
66,591
DOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
