Rare disease
29 Aug 2025 : Case report 
Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report
Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang
DOI: 10.12659/AJCR.948422
Am J Case Rep 2025; 26:e948422
349 1,088 0
29 Aug 2025 : Case report
Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report
Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang
DOI: 10.12659/AJCR.948422
Am J Case Rep 2025; 26:e948422
349 1088 0
25 Aug 2025 : Case report 
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Rina Kobayashi, Tomohide Hori 
, Makoto Yamawaki, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shinichiro Atsumi, Hiroshi Hasegawa, Shigehito Nakashima, Kunihiro Higuchi, Kentaro Onishi, Ryotaro Sakaguchi, Shoichi Morita, Haruka Miyao, Saki Aota, Hikaru Ohtani, Takayuki Yamamoto
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
574 1,027 0
25 Aug 2025 : Case report
Rapid Progression of Primary Hepatic Neuroendocrine Carcinoma: A Case Report Demonstrating Drastic Oncological Behavior
Rina Kobayashi, Tomohide Hori , Makoto Yamawaki, Shigeki Nakayama, Satoru Umegae, Takao Iwanaga, Ryutaro Nishikawa, Takahiro Shimoyama, Sakurako Suzuki, Shinichiro Atsumi, Hiroshi Hasegawa, Shigehito Nakashima, Kunihiro Higuchi, Kentaro Onishi, Ryotaro Sakaguchi, Shoichi Morita, Haruka Miyao, Saki Aota, Hikaru Ohtani, Takayuki Yamamoto
DOI: 10.12659/AJCR.948500
Am J Case Rep 2025; 26:e948500
574 1027 0
25 Aug 2025 : Case report
Two Cases of Charcot-Marie-Tooth Disease Diagnosed in a 53-Year-Old Mother and a 24-Year-Old Daughter
Junying Zhu, Shimiao Dai, Yao Li, Miaomiao Ma, Ming Chu, ZhiQiang Lin , Litao Sun , Ji-Chang Zhou
DOI: 10.12659/AJCR.947400
Am J Case Rep 2025; 26:e947400
679 1,360 0
25 Aug 2025 : Case report
Two Cases of Charcot-Marie-Tooth Disease Diagnosed in a 53-Year-Old Mother and a 24-Year-Old Daughter
Junying Zhu, Shimiao Dai, Yao Li, Miaomiao Ma, Ming Chu, ZhiQiang Lin , Litao Sun , Ji-Chang Zhou
DOI: 10.12659/AJCR.947400
Am J Case Rep 2025; 26:e947400
679 1360 0
23 Aug 2025 : Case report 
Management of Cardiac Tamponade During Systemic Lupus Erythematosus Flare with Significant Pericardial Effusion: A Case Report
Adam D. Walsh , Mitchell T. Carroll
DOI: 10.12659/AJCR.947859
Am J Case Rep 2025; 26:e947859
631 2,045 0
23 Aug 2025 : Case report
Management of Cardiac Tamponade During Systemic Lupus Erythematosus Flare with Significant Pericardial Effusion: A Case Report
Adam D. Walsh , Mitchell T. Carroll
DOI: 10.12659/AJCR.947859
Am J Case Rep 2025; 26:e947859
631 2045 0
20 Aug 2025 : Case report 
Uncommon Ileo-Cecal Intussusception in Adults: A Case Report of Diagnosis and Management
Yembu Ngwengi , Christian Beugheum, Christian Ottou, Benjamin Freddy Mindjeme, Jacqueline Soh, Roger Ngoulla
DOI: 10.12659/AJCR.946853
Am J Case Rep 2025; 26:e946853
525 753 0
20 Aug 2025 : Case report
Uncommon Ileo-Cecal Intussusception in Adults: A Case Report of Diagnosis and Management
Yembu Ngwengi , Christian Beugheum, Christian Ottou, Benjamin Freddy Mindjeme, Jacqueline Soh, Roger Ngoulla
DOI: 10.12659/AJCR.946853
Am J Case Rep 2025; 26:e946853
525 753 0
13 Aug 2025 : Case report 
Pulmonic Valve Endocarditis and Septic Pulmonary Embolism Caused by Staphylococcus haemolyticus: A Case Study
Sneh Parekh , Guillermo Loyola, Ricardo A. Caldas, Hamza Choudhry, Emma M. Griffith
DOI: 10.12659/AJCR.948820
Am J Case Rep 2025; 26:e948820
573 1,466 0
13 Aug 2025 : Case report
Pulmonic Valve Endocarditis and Septic Pulmonary Embolism Caused by Staphylococcus haemolyticus: A Case Study
Sneh Parekh , Guillermo Loyola, Ricardo A. Caldas, Hamza Choudhry, Emma M. Griffith
DOI: 10.12659/AJCR.948820
Am J Case Rep 2025; 26:e948820
573 1466 0
14 Aug 2025 : Case report 
A 66-Year-Old Man with Intrapleural Leakage of Parenteral Nutrition Fluid Due to a Malpositioned Central Venous Catheter
Jakob Van Herck, Wouter Snoeck, Marc Vanhoof, Helena Van Damme, Lynn Decoster
DOI: 10.12659/AJCR.948181
Am J Case Rep 2025; 26:e948181
1,212 886 0
14 Aug 2025 : Case report
A 66-Year-Old Man with Intrapleural Leakage of Parenteral Nutrition Fluid Due to a Malpositioned Central Venous Catheter
Jakob Van Herck, Wouter Snoeck, Marc Vanhoof, Helena Van Damme, Lynn Decoster
DOI: 10.12659/AJCR.948181
Am J Case Rep 2025; 26:e948181
1212 886 0
18 Aug 2025 : Case report 
Crucial Role of Early Detection in Managing Heart Failure in Kearns-Sayre Syndrome: A Case Report
Dominik Krupka , Katarzyna Rakoczy , Adam Chełmoński , Michał Zakliczyński , Roman Przybylski , Mateusz Sokolski
DOI: 10.12659/AJCR.947439
Am J Case Rep 2025; 26:e947439
583 863 0
18 Aug 2025 : Case report
Crucial Role of Early Detection in Managing Heart Failure in Kearns-Sayre Syndrome: A Case Report
Dominik Krupka , Katarzyna Rakoczy , Adam Chełmoński , Michał Zakliczyński , Roman Przybylski , Mateusz Sokolski
DOI: 10.12659/AJCR.947439
Am J Case Rep 2025; 26:e947439
583 863 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
421 1,228 0
15 Aug 2025 : Case report
HELLP Syndrome with Hepatic and Thoracic Complications: Insights From a Case of Spontaneous Liver Rupture
Sanqiang Niu, Kangjun Yu, Yayun Cheng, Ning Liu
DOI: 10.12659/AJCR.949380
Am J Case Rep 2025; 26:e949380
421 1228 0
10 Aug 2025 : Case report
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni , Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
855 848 0
10 Aug 2025 : Case report
Disseminated Blastomycosis: A Case of Multisite Infection in an Immunocompetent Patient
Vishnu Teja Kommineni , Joshua J. Jagodzinski, Emilia Elena Petcu, Celestine Odenigbo, Rathnamitreyee Vegunta , Igor Dumic
DOI: 10.12659/AJCR.949647
Am J Case Rep 2025; 26:e949647
855 848 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
691 739 0
09 Aug 2025 : Case report
Primary Adrenal Lymphoma Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration Biopsy: A Case Report
Yuzheng Zhao, Ning Chen
DOI: 10.12659/AJCR.948833
Am J Case Rep 2025; 26:e948833
691 739 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
753 740 0
06 Aug 2025 : Case report
Unveiling Maternal Germline Mosaicism in X-Linked Alport Syndrome by Advanced Genetic Testing
Yuting Shen, Caihong Liu, Wei Wei, Yongxiu Huang , Qian Zhu, Yuliang Zhao
DOI: 10.12659/AJCR.947287
Am J Case Rep 2025; 26:e947287
753 740 0
04 Aug 2025 : Case report 
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
697 1,105 0
04 Aug 2025 : Case report
Visceral Arterial Thrombosis Linked to Long-Term Oral Contraceptives and Smoking: A Case Report
Laura Leci Tahiri, Valdete Haxhibeqiri
DOI: 10.12659/AJCR.948398
Am J Case Rep 2025; 26:e948398
697 1105 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
899 1,316 0
30 Jul 2025 : Case report
Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis
Mengqi Guan, Yan Qian, Zihua Tang, Yingya Cao, Xiaogan Jiang, Weihua Lu, Qiancheng Xu
DOI: 10.12659/AJCR.949154
Am J Case Rep 2025; 26:e949154
899 1316 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
850 1,534 0
24 Jul 2025 : Case report
Ectopic Adrenocortical Adenoma Causing Malignant Hypertension and Hypokalemia
Xiaoyong Hu , Djandan Tadum Arthur Vithran , Zhaoying Yang, Hongjian Li
DOI: 10.12659/AJCR.948022
Am J Case Rep 2025; 26:e948022
850 1534 0
23 Jul 2025 : Case report 
Percutaneous Closure of an Ischemic Ventricular Septal Rupture in a 73-Year-Old Man: A Case Report
Carlos Andres Mejia-Gomez , Paula Andrea Cardenas Marin , Maria Juliana Reyes-Cardona , Miller Giraldo-Sandoval , Camilo Andres Calderon-Miranda , Jorge Alexander Zambrano-Franco , Pastor Olaya , Jairo Sanchez-Blanco , Carlos Enrique Vesga-Reyes
DOI: 10.12659/AJCR.947065
Am J Case Rep 2025; 26:e947065
783 1,149 0
23 Jul 2025 : Case report
Percutaneous Closure of an Ischemic Ventricular Septal Rupture in a 73-Year-Old Man: A Case Report
Carlos Andres Mejia-Gomez , Paula Andrea Cardenas Marin , Maria Juliana Reyes-Cardona , Miller Giraldo-Sandoval , Camilo Andres Calderon-Miranda , Jorge Alexander Zambrano-Franco , Pastor Olaya , Jairo Sanchez-Blanco , Carlos Enrique Vesga-Reyes
DOI: 10.12659/AJCR.947065
Am J Case Rep 2025; 26:e947065
783 1149 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
742 1,136 0
21 Jul 2025 : Case report
Diagnosing Disseminated Peritoneal Leiomyomatosis: Malignancy-Like Presentation in a 59-Year-Old Woman
Changchao Xiao, Haixing Ju, Jun Cao
DOI: 10.12659/AJCR.947246
Am J Case Rep 2025; 26:e947246
742 1136 0
19 Jul 2025 : Case report
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1,309 1,629 0
19 Jul 2025 : Case report
Adult Hemophagocytic Lymphohistiocytosis (HLH) with Neurological Involvement: Diagnostic Complexities – A Case Report and Literature Review
Michał J. Sekuła , Anna Jamroz-Wiśniewska , Urszula Chyrchel-Paszkiewicz , Aleksandra Pietruczuk , Aleksandra Dembowska , Maciej Dubaj , Karol Bigosiński , Konrad Rejdak
DOI: 10.12659/AJCR.947694
Am J Case Rep 2025; 26:e947694
1309 1629 0
18 Jul 2025 : Case report
An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellular Carcinoma Treated with Carbon-Ion Radiotherapy
Akira Sato, Reiko Kumano, Yasushi Ariizumi, Nobuyuki Matsumoto
DOI: 10.12659/AJCR.947725
Am J Case Rep 2025; 26:e947725
931 1,398 0
18 Jul 2025 : Case report
An 88-Year-Old Woman with a 33-Year History of Idiopathic Portal Hypertension Presenting with Hepatocellular Carcinoma Treated with Carbon-Ion Radiotherapy
Akira Sato, Reiko Kumano, Yasushi Ariizumi, Nobuyuki Matsumoto
DOI: 10.12659/AJCR.947725
Am J Case Rep 2025; 26:e947725
931 1398 0
16 Jul 2025 : Case report 
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
839 1,351 0
16 Jul 2025 : Case report
Endovascular Embolization in Acquired Hemophilia A: A Case Study Highlighting Diagnostic and Therapeutic Strategies
Michail Makris, Stavroula Bountola, Vasileios Patriarcheas, Anastasia Adamou , Panagiota Tsiatsiou , Vasileios Perifanis , Christos Savopoulos, Georgia Kaiafa
DOI: 10.12659/AJCR.948268
Am J Case Rep 2025; 26:e948268
839 1351 0
13 Jul 2025 : Case report 
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
709 1,426 0
13 Jul 2025 : Case report
Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis
Daniel Krstic , Dimitrios Chatziisaak , Strahinja Konstantinović , Luca Benigno, Christopher Soll, Magdalena Biraima
DOI: 10.12659/AJCR.949194
Am J Case Rep 2025; 26:e949194
709 1426 0
12 Jul 2025 : Case report 
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
795 1,481 0
12 Jul 2025 : Case report
HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report
Vaishnavi Ghantasala, Aadi Palvia, Abhiram Rao Damera, Marcela Salomao, Lucinda A. Harris, Jana G. Hashash, Karthik Gnanapandithan
DOI: 10.12659/AJCR.947163
Am J Case Rep 2025; 26:e947163
795 1481 0
11 Jul 2025 : Case report 
Term Pregnancy in Herlyn-Werner-Wunderlich Syndrome: Successful Management of Congenital Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA)
Norah Alqntash , Ebtesam Almajed , Kayan Alotaibi, Mashael Alshahrani, Yara Arfaj, Rawda Albahyan
DOI: 10.12659/AJCR.947938
Am J Case Rep 2025; 26:e947938
589 1,039 0
11 Jul 2025 : Case report
Term Pregnancy in Herlyn-Werner-Wunderlich Syndrome: Successful Management of Congenital Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA)
Norah Alqntash , Ebtesam Almajed , Kayan Alotaibi, Mashael Alshahrani, Yara Arfaj, Rawda Albahyan
DOI: 10.12659/AJCR.947938
Am J Case Rep 2025; 26:e947938
589 1039 0
09 Jul 2025 : Case report
Selective IgA Deficiency Complicated with Pernicious Anemia Diagnosed After Febrile Non-Hemolytic Transfusion Reaction
Yuta Yoshino , Natsumi Kosugi
DOI: 10.12659/AJCR.947678
Am J Case Rep 2025; 26:e947678
850 2,340 0
09 Jul 2025 : Case report
Selective IgA Deficiency Complicated with Pernicious Anemia Diagnosed After Febrile Non-Hemolytic Transfusion Reaction
Yuta Yoshino , Natsumi Kosugi
DOI: 10.12659/AJCR.947678
Am J Case Rep 2025; 26:e947678
850 2340 0
06 Jul 2025 : Case report
Bowel Ischemia as a Rare Manifestation of Extracranial Moyamoya Disease: A Case Report
Sameera Shuaibi, Najat AlSejari, Ian Tobal, Reinaldo Quevedo
DOI: 10.12659/AJCR.949530
Am J Case Rep 2025; 26:e949530
735 1,029 0
06 Jul 2025 : Case report
Bowel Ischemia as a Rare Manifestation of Extracranial Moyamoya Disease: A Case Report
Sameera Shuaibi, Najat AlSejari, Ian Tobal, Reinaldo Quevedo
DOI: 10.12659/AJCR.949530
Am J Case Rep 2025; 26:e949530
735 1029 0
In Press
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.949976
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950290
Case report 
Am J Case Rep In Press; DOI: 10.12659/AJCR.950607
Case report
Am J Case Rep In Press; DOI: 10.12659/AJCR.950985
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