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Unusual or unexpected effect of treatment

#947844

23 Mar 2026 : Case report  Indonesia

Isolated Premature Menarche in a 17-Month-Old: A Case Report

Dewi Rani Pelitawati ORCID logo, Artha Falentin Putri Susilo ORCID logo, Anita Rachmawati ORCID logo, Wiryawan Permadi ORCID logo, Putri Nadhira Adinda Adriansyah ORCID logo, Nabila Chantikarizky Hasanah ORCID logo

DOI: 10.12659/AJCR.947844

Am J Case Rep 2026; 27:e947844

922 3,042 0

#947844

23 Mar 2026 : Case report  Indonesia

Isolated Premature Menarche in a 17-Month-Old: A Case Report

Dewi Rani Pelitawati ORCID logo, Artha Falentin Putri Susilo ORCID logo, Anita Rachmawati ORCID logo, Wiryawan Permadi ORCID logo, Putri Nadhira Adinda Adriansyah ORCID logo, Nabila Chantikarizky Hasanah ORCID logo

DOI: 10.12659/AJCR.947844

Am J Case Rep 2026; 27:e947844

922 3042 0

#950915

21 Mar 2026 : Case report  Japan

Janus Kinase Inhibitor Upadacitinib in Elderly-Onset Rheumatoid Arthritis With Hip Osteoarthritis: A Case Report

Yusuke Sanji, Isao Matsushita, Eiji Takahashi, Makoto Fukui, Hironori Kitajima ORCID logo, Ayumi Kaneuji

DOI: 10.12659/AJCR.950915

Am J Case Rep 2026; 27:e950915

781 1,330 0

#950915

21 Mar 2026 : Case report  Japan

Janus Kinase Inhibitor Upadacitinib in Elderly-Onset Rheumatoid Arthritis With Hip Osteoarthritis: A Case Report

Yusuke Sanji, Isao Matsushita, Eiji Takahashi, Makoto Fukui, Hironori Kitajima ORCID logo, Ayumi Kaneuji

DOI: 10.12659/AJCR.950915

Am J Case Rep 2026; 27:e950915

781 1330 0

#951570

19 Mar 2026 : Case report  Thailand

Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report

Kitiwan Rojnueangnit ORCID logo, Sukita Puttamanee ORCID logo, Sukkrawan Intarakhao, Khanittha Khusiwilai ORCID logo

DOI: 10.12659/AJCR.951570

Am J Case Rep 2026; 27:e951570

875 1,724 0

#951570

19 Mar 2026 : Case report  Thailand

Early Diagnosis of Nieman–Pick Disease Type C and Rapid Response of Gelastic Cataplexy to Treatment With N-Acetyl-L-Leucine: A Case Report

Kitiwan Rojnueangnit ORCID logo, Sukita Puttamanee ORCID logo, Sukkrawan Intarakhao, Khanittha Khusiwilai ORCID logo

DOI: 10.12659/AJCR.951570

Am J Case Rep 2026; 27:e951570

875 1724 0

#951067

18 Mar 2026 : Case report  USA

Therapeutic Use of Melatonin for Gastrointestinal Motility and Hypersomnolence in a Patient With Pineal Cyst Pathology

Austin R. Cross, Julia R. Van Liew ORCID logo, Poojan Thakkar ORCID logo, Autumn Brunia ORCID logo

DOI: 10.12659/AJCR.951067

Am J Case Rep 2026; 27:e951067

959 2,469 0

#951067

18 Mar 2026 : Case report  USA

Therapeutic Use of Melatonin for Gastrointestinal Motility and Hypersomnolence in a Patient With Pineal Cyst Pathology

Austin R. Cross, Julia R. Van Liew ORCID logo, Poojan Thakkar ORCID logo, Autumn Brunia ORCID logo

DOI: 10.12659/AJCR.951067

Am J Case Rep 2026; 27:e951067

959 2469 0

#950688

17 Mar 2026 : Case report  Saudi Arabia

Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review

Manar Abdullah Makin, Ahmed Hussein Subki ORCID logo, Manal Ismail Bokhary

DOI: 10.12659/AJCR.950688

Am J Case Rep 2026; 27:e950688

881 1,847 0

#950688

17 Mar 2026 : Case report  Saudi Arabia

Linezolid-Associated Triad of Acute Pancreatitis, Lactic Acidosis, and Hypoglycemia: A Rare Case Report and Literature Review

Manar Abdullah Makin, Ahmed Hussein Subki ORCID logo, Manal Ismail Bokhary

DOI: 10.12659/AJCR.950688

Am J Case Rep 2026; 27:e950688

881 1847 0

#950833

15 Mar 2026 : Case report  China

Significant Improvement in High Myopic Anisometropic Amblyopia Treated With Repeated Low-Level Red-Light (RLRL) Therapy: A Case Report

Qiu-Jian Zhu, Jian-Jun Liu, Lan-Jun Niu, Guang-Hui Zhao

DOI: 10.12659/AJCR.950833

Am J Case Rep 2026; 27:e950833

944 2,629 0

#950833

15 Mar 2026 : Case report  China

Significant Improvement in High Myopic Anisometropic Amblyopia Treated With Repeated Low-Level Red-Light (RLRL) Therapy: A Case Report

Qiu-Jian Zhu, Jian-Jun Liu, Lan-Jun Niu, Guang-Hui Zhao

DOI: 10.12659/AJCR.950833

Am J Case Rep 2026; 27:e950833

944 2629 0

#950337

11 Mar 2026 : Case report  China

Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths

Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li

DOI: 10.12659/AJCR.950337

Am J Case Rep 2026; 27:e950337

895 1,911 0

#950337

11 Mar 2026 : Case report  China

Capsaicin-Triggered Vaginal Burning Due to Obstructed Rectovaginal Fistula: A Rare Case of Perineal Coproliths

Yujiao Wu, Weizheng Huang, Yong Wen, Cengzi Huang, Yaling Li, Jun Li

DOI: 10.12659/AJCR.950337

Am J Case Rep 2026; 27:e950337

895 1911 0

#950992

09 Mar 2026 : Case report  China

Recurrent Eosinophilic Pancreatitis With Eosinophilic Gastroenteritis: A Case Report

Xinyu Li, Donglei Zhang, Yanchen Li, Kunning Zhang, Ning Li

DOI: 10.12659/AJCR.950992

Am J Case Rep 2026; 27:e950992

734 2,039 0

#950992

09 Mar 2026 : Case report  China

Recurrent Eosinophilic Pancreatitis With Eosinophilic Gastroenteritis: A Case Report

Xinyu Li, Donglei Zhang, Yanchen Li, Kunning Zhang, Ning Li

DOI: 10.12659/AJCR.950992

Am J Case Rep 2026; 27:e950992

734 2039 0

#950618

09 Mar 2026 : Case report  USA

Endovascular Coil Migration to Duodenal Lumen After Gastroduodenal Artery Embolization in a 90-Year-Old-Woman, Complicating Upper-GI Bleed Management: A Case Report

Taylor A. Hagans ORCID logo, Lauren Canaff, Ryan Rimer, Frank J. Nemec

DOI: 10.12659/AJCR.950618

Am J Case Rep 2026; 27:e950618

679 1,805 0

#950618

09 Mar 2026 : Case report  USA

Endovascular Coil Migration to Duodenal Lumen After Gastroduodenal Artery Embolization in a 90-Year-Old-Woman, Complicating Upper-GI Bleed Management: A Case Report

Taylor A. Hagans ORCID logo, Lauren Canaff, Ryan Rimer, Frank J. Nemec

DOI: 10.12659/AJCR.950618

Am J Case Rep 2026; 27:e950618

679 1805 0

#950857

07 Mar 2026 : Case report  Norway

Cryoglobulinemia Type II: Sustained Remission After B-Cell–Directed Therapy

Sara Giæver Suul ORCID logo, Ann Kristin Kvam, Malu Lian Hestdalen, Ulla Randen ORCID logo, Øyvind Midtvedt, Geir E. Tjønnfjord

DOI: 10.12659/AJCR.950857

Am J Case Rep 2026; 27:e950857

737 1,818 0

#950857

07 Mar 2026 : Case report  Norway

Cryoglobulinemia Type II: Sustained Remission After B-Cell–Directed Therapy

Sara Giæver Suul ORCID logo, Ann Kristin Kvam, Malu Lian Hestdalen, Ulla Randen ORCID logo, Øyvind Midtvedt, Geir E. Tjønnfjord

DOI: 10.12659/AJCR.950857

Am J Case Rep 2026; 27:e950857

737 1818 0

#951172

06 Mar 2026 : Case report  China

Multifocal Digital Squamous Cell Carcinoma With Sarcoma Differentiation: A Case Report

Yingling Xiang, Liuchang Tan

DOI: 10.12659/AJCR.951172

Am J Case Rep 2026; 27:e951172

781 2,144 0

#951172

06 Mar 2026 : Case report  China

Multifocal Digital Squamous Cell Carcinoma With Sarcoma Differentiation: A Case Report

Yingling Xiang, Liuchang Tan

DOI: 10.12659/AJCR.951172

Am J Case Rep 2026; 27:e951172

781 2144 0

#950820

05 Mar 2026 : Case report  Poland

Bilateral Eales’ Disease Managed With Vitrectomy and Anti-VEGF Therapy: A Case Report

Zuzanna Lelek ORCID logo, Martyna Machaj ORCID logo, Katarzyna Krysik ORCID logo, Dominika Janiszewska-Bil ORCID logo, Dariusz Dobrowolski ORCID logo, Sylwia Ewa Szendzielorz-Krzempek, Beniamin Oskar Grabarek ORCID logo, Anita Lyssek-Boroń ORCID logo

DOI: 10.12659/AJCR.950820

Am J Case Rep 2026; 27:e950820

783 1,690 0

#950820

05 Mar 2026 : Case report  Poland

Bilateral Eales’ Disease Managed With Vitrectomy and Anti-VEGF Therapy: A Case Report

Zuzanna Lelek ORCID logo, Martyna Machaj ORCID logo, Katarzyna Krysik ORCID logo, Dominika Janiszewska-Bil ORCID logo, Dariusz Dobrowolski ORCID logo, Sylwia Ewa Szendzielorz-Krzempek, Beniamin Oskar Grabarek ORCID logo, Anita Lyssek-Boroń ORCID logo

DOI: 10.12659/AJCR.950820

Am J Case Rep 2026; 27:e950820

783 1690 0

#949653

05 Mar 2026 : Case report  Italy

Leukocytoclastic Vasculitis Induced by Dalbavancin: A Case Report

Vincenzo Scaglione ORCID logo, Marco Cola, Lolita Sasset, Francesco Fortarezza ORCID logo, Carla Casarin, Marco Trevenzoli, Angelo Paolo Dei Tos, Annamaria Cattelan

DOI: 10.12659/AJCR.949653

Am J Case Rep 2026; 27:e949653

780 1,736 0

#949653

05 Mar 2026 : Case report  Italy

Leukocytoclastic Vasculitis Induced by Dalbavancin: A Case Report

Vincenzo Scaglione ORCID logo, Marco Cola, Lolita Sasset, Francesco Fortarezza ORCID logo, Carla Casarin, Marco Trevenzoli, Angelo Paolo Dei Tos, Annamaria Cattelan

DOI: 10.12659/AJCR.949653

Am J Case Rep 2026; 27:e949653

780 1736 0

#948944

04 Mar 2026 : Case report  Saudi Arabia

Reduced Accommodation Without Mydriasis After Micropulse Cyclophotocoagulation in a Young Congenital Glaucoma Patient: A Case Report

Meznah H. Alsanad, Reem M. Hersi ORCID logo, Sami Alshahwan, Furat Alrajhi ORCID logo

DOI: 10.12659/AJCR.948944

Am J Case Rep 2026; 27:e948944

662 1,245 0

#948944

04 Mar 2026 : Case report  Saudi Arabia

Reduced Accommodation Without Mydriasis After Micropulse Cyclophotocoagulation in a Young Congenital Glaucoma Patient: A Case Report

Meznah H. Alsanad, Reem M. Hersi ORCID logo, Sami Alshahwan, Furat Alrajhi ORCID logo

DOI: 10.12659/AJCR.948944

Am J Case Rep 2026; 27:e948944

662 1245 0

#951215

01 Mar 2026 : Case report  China

Primary Aldosteronism Causing Aortic Dissection: A Case Report

Quan Zuo, Li Zhao ORCID logo, Tao Ge

DOI: 10.12659/AJCR.951215

Am J Case Rep 2026; 27:e951215

835 1,546 0

#951215

01 Mar 2026 : Case report  China

Primary Aldosteronism Causing Aortic Dissection: A Case Report

Quan Zuo, Li Zhao ORCID logo, Tao Ge

DOI: 10.12659/AJCR.951215

Am J Case Rep 2026; 27:e951215

835 1546 0

#949272

26 Feb 2026 : Case report  Colombia

Diagnostic and Therapeutic Approaches to Pediatric Pulmonary Abscess: A Case Report

Jhon Camacho-Cruz ORCID logo, María Victoria Alfonso-Hernández ORCID logo, Marieta Arjona-Quintero ORCID logo, William Ricardo Bachiller-Tuta ORCID logo, Maria Luisa Beltran-Echeverry ORCID logo

DOI: 10.12659/AJCR.949272

Am J Case Rep 2026; 27:e949272

772 2,034 0

#949272

26 Feb 2026 : Case report  Colombia

Diagnostic and Therapeutic Approaches to Pediatric Pulmonary Abscess: A Case Report

Jhon Camacho-Cruz ORCID logo, María Victoria Alfonso-Hernández ORCID logo, Marieta Arjona-Quintero ORCID logo, William Ricardo Bachiller-Tuta ORCID logo, Maria Luisa Beltran-Echeverry ORCID logo

DOI: 10.12659/AJCR.949272

Am J Case Rep 2026; 27:e949272

772 2034 0

#949860

22 Feb 2026 : Case report  USA

Pulmonary Embolism and Right Heart Failure Associated With Lipomatous Atrial Septal Hypertrophy: A Case Report

Prutha Pathak, Siddharth Patel ORCID logo, Amogh Reddy, Jason Mathew, Ashish Basu, Mrudula Thiriveedi, Sujatha Baddam ORCID logo

DOI: 10.12659/AJCR.949860

Am J Case Rep 2026; 27:e949860

898 1,458 0

#949860

22 Feb 2026 : Case report  USA

Pulmonary Embolism and Right Heart Failure Associated With Lipomatous Atrial Septal Hypertrophy: A Case Report

Prutha Pathak, Siddharth Patel ORCID logo, Amogh Reddy, Jason Mathew, Ashish Basu, Mrudula Thiriveedi, Sujatha Baddam ORCID logo

DOI: 10.12659/AJCR.949860

Am J Case Rep 2026; 27:e949860

898 1458 0

#951269

20 Feb 2026 : Case report  Australia

Fatal Status Epilepticus After Elective Revision Cranioplasty: Case Report and Literature Review

Kate Spuler, Lola Kaukas ORCID logo, Samuel Tawfik ORCID logo, Adam Wells

DOI: 10.12659/AJCR.951269

Am J Case Rep 2026; 27:e951269

931 2,068 0

#951269

20 Feb 2026 : Case report  Australia

Fatal Status Epilepticus After Elective Revision Cranioplasty: Case Report and Literature Review

Kate Spuler, Lola Kaukas ORCID logo, Samuel Tawfik ORCID logo, Adam Wells

DOI: 10.12659/AJCR.951269

Am J Case Rep 2026; 27:e951269

931 2068 0

#951064

17 Feb 2026 : Case report  United Arab Emirates

Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability

Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali

DOI: 10.12659/AJCR.951064

Am J Case Rep 2026; 27:e951064

1,288 3,348 0

#951064

17 Feb 2026 : Case report  United Arab Emirates

Anti-MDA5 Antibody-Positive Dermatomyositis in Emirati Patients: A Case Series Highlighting Clinical Variability

Deena Ahmed, Khulood Khawaja, Afra Al Dhaheri, Abdulla Alshamsi, Amna Almheiri, Ahlam Almarzooqi, Sarah Al Qassimi, Rajaie Namas, Gehad ElGhazali

DOI: 10.12659/AJCR.951064

Am J Case Rep 2026; 27:e951064

1288 3348 0

#950275

15 Feb 2026 : Case report  Italy

Refractory Primary Immune Thrombocytopenia With Bleeding and Thrombosis: A Case Report

Veronica Vecchio ORCID logo, Uros Markovic, Stephanie Grasso, Antonella Nardo, Gaetano Giuffrida

DOI: 10.12659/AJCR.950275

Am J Case Rep 2026; 27:e950275

1,237 2,873 0

#950275

15 Feb 2026 : Case report  Italy

Refractory Primary Immune Thrombocytopenia With Bleeding and Thrombosis: A Case Report

Veronica Vecchio ORCID logo, Uros Markovic, Stephanie Grasso, Antonella Nardo, Gaetano Giuffrida

DOI: 10.12659/AJCR.950275

Am J Case Rep 2026; 27:e950275

1237 2873 0

#951026

14 Feb 2026 : Case report  Qatar

Methylene Blue Rescue Therapy for Vasoplegic Shock After Antihypertensive Drug Overdose

Yousef H.I. Aqel ORCID logo, Monder Mustafa Jebril Karayem ORCID logo, Alaa Rahhal ORCID logo, Sunil Hasan Koya ORCID logo, Abdelaziz Maali Abusal, Saibu George

DOI: 10.12659/AJCR.951026

Am J Case Rep 2026; 27:e951026

1,085 3,705 0

#951026

14 Feb 2026 : Case report  Qatar

Methylene Blue Rescue Therapy for Vasoplegic Shock After Antihypertensive Drug Overdose

Yousef H.I. Aqel ORCID logo, Monder Mustafa Jebril Karayem ORCID logo, Alaa Rahhal ORCID logo, Sunil Hasan Koya ORCID logo, Abdelaziz Maali Abusal, Saibu George

DOI: 10.12659/AJCR.951026

Am J Case Rep 2026; 27:e951026

1085 3705 0

#951331

12 Feb 2026 : Case report  USA

Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report

Abhinav Singla ORCID logo, Asmita Addanki ORCID logo, Aleena Shahnawaz ORCID logo, Alyssa Catherine Raj ORCID logo, Anam Sadia, Shah Rukh, Muhammad Ali ORCID logo, Aleksandra Murawska Baptista ORCID logo

DOI: 10.12659/AJCR.951331

Am J Case Rep 2026; 27:e951331

925 1,670 0

#951331

12 Feb 2026 : Case report  USA

Bilateral Adrenal Infarction as an Uncommon Complication of Heparin-Induced Thrombocytopenia: A Case Report

Abhinav Singla ORCID logo, Asmita Addanki ORCID logo, Aleena Shahnawaz ORCID logo, Alyssa Catherine Raj ORCID logo, Anam Sadia, Shah Rukh, Muhammad Ali ORCID logo, Aleksandra Murawska Baptista ORCID logo

DOI: 10.12659/AJCR.951331

Am J Case Rep 2026; 27:e951331

925 1670 0

#951061

11 Feb 2026 : Case report  China

Secondary Thoracoabdominal Aortic Replacement Following Total Arch Repair With a Sutureless Integrated Stented Graft in Marfan Syndrome: A Case Report

Yumeng Ji, Juntao Qiu, Ying Liu, Bin Hou, Fang Li, Cuntao Yu

DOI: 10.12659/AJCR.951061

Am J Case Rep 2026; 27:e951061

632 1,228 0

#951061

11 Feb 2026 : Case report  China

Secondary Thoracoabdominal Aortic Replacement Following Total Arch Repair With a Sutureless Integrated Stented Graft in Marfan Syndrome: A Case Report

Yumeng Ji, Juntao Qiu, Ying Liu, Bin Hou, Fang Li, Cuntao Yu

DOI: 10.12659/AJCR.951061

Am J Case Rep 2026; 27:e951061

632 1228 0

#950084

09 Feb 2026 : Case report  China

Successful Treatment of Multifocal Demyelinating Sensory-Motor Neuropathy (Lewis-Sumner Syndrome) With Rituximab: A Case Report

Mengcui Gui, Jing Lin, Yue Li ORCID logo, Bo Chen, Bitao Bu, Zhijun Li

DOI: 10.12659/AJCR.950084

Am J Case Rep 2026; 27:e950084

1,345 6,304 0

#950084

09 Feb 2026 : Case report  China

Successful Treatment of Multifocal Demyelinating Sensory-Motor Neuropathy (Lewis-Sumner Syndrome) With Rituximab: A Case Report

Mengcui Gui, Jing Lin, Yue Li ORCID logo, Bo Chen, Bitao Bu, Zhijun Li

DOI: 10.12659/AJCR.950084

Am J Case Rep 2026; 27:e950084

1345 6304 0

#951125

04 Feb 2026 : Case report  China

Two-Stage Approach and Minimally Invasive Vitrectomy for Severe Ocular Perforation Injury: A Case Report

Wendie Li, Jinghai Mao

DOI: 10.12659/AJCR.951125

Am J Case Rep 2026; 27:e951125

525 1,259 0

#951125

04 Feb 2026 : Case report  China

Two-Stage Approach and Minimally Invasive Vitrectomy for Severe Ocular Perforation Injury: A Case Report

Wendie Li, Jinghai Mao

DOI: 10.12659/AJCR.951125

Am J Case Rep 2026; 27:e951125

525 1259 0

In Press

Case report  Japan

A 78-Year-Old Man With a Previously Stable Atherosclerotic Abdominal Aortic Aneurysm Presenting With Impend...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954216  

Case report  China

Tricuspid Chordae Tendineae Rupture Detected After Repair of a Delayed Traumatic Left Ventricular Aneurysm:...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954932  

Case report  USA

Bilateral Xanthogranulomatous Pyelonephritis in a Patient With Spina Bifida and Neurogenic Bladder: A Case ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.954146  

Case report  China

Testis-Sparing Surgery for Multiple Fibrous Pseudotumors of the Epididymis: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.953555  

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923