20 April 2004
Omental transplantation for type 2 diabetes mellitus. A report of two cases
Wilfredo García, Pedro Moromizato, Rafaela Mego, Hernando Rafael, José RodriguezCase Rep Clin Pract Rev 2004; 5(null):481-486 :: ID: 12356
Abstract
Background: Since 1997 we known that the revascularization in the posterior hypothalamic nuclei can normalize neurogenic hypertension and likewise,experimental and clinical studies suggest that
type 2 diabetes mellitus (DM) is a disorder of the hypothalamus.Case Report: Case 1 was a 75-year-old woman with type 2 DM,vertigo,mild Alzheimer´s disease(AD), olfactory deficit and daytime sleepiness. During 10 years with diabetes,her blood glucose fluctuated between 110 and 240 mg %. Case 2 is a 82-year-old man with a 14-year history of type 2 DM,and lately,he presented motor deficit,bladder dysfunction,arterial hypertension,visual impairment and siallorrhea. His glycemias varied between 115 and 175 mg%. Both patientswere treated with oral hypoglycemic agents. An omental transplantation on the optic chiasma and the carotid bifurcation was performed on both cases.Results: Neurological improvement began since the first days after the operation; especially the mild AD disappeared and neurogenic hypertension was normalized and without antihypertensive medication. Moreover ,they had normal levels of circulating blood glucose and with scarce antidiabetic medication.Conclusions: These neurosurgical findings indicate that ischemic neurons in the anterior hypothalamic nuclei are responsibles at the onset of type 2 DM( mild state ).
Keywords: Cerebral atherosclerosis, Hypothalamic ischemia, Omental transplantation., type 2 diabetes
47
In Press
16 Mar 2024 : Case report
Castleman Disease Presenting in the Neck: A Report of 3 Cases and a Literature ReviewAm J Case Rep In Press; DOI: 10.12659/AJCR.943214
16 Mar 2024 : Case report
Early Diagnosis and Successful Empirical Treatment of L1-L2 Spondylodiscitis in a 21-Month-Old Girl: A Case...Am J Case Rep In Press; DOI: 10.12659/AJCR.943010
16 Mar 2024 : Case report
A Rare Autochthonous Case of Hepatic Hydatid Cyst in the Non-Endemic Region of TaiwanAm J Case Rep In Press; DOI: 10.12659/AJCR.943687
17 Mar 2024 : Case report
Contrast-Enhanced Ultrasonography in Diagnosing Intravascular Large B-Cell Lymphoma Infiltrating Liver Sinu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943070
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250