Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

20 April 2004

Omental transplantation for type 2 diabetes mellitus. A report of two cases

Wilfredo García, Pedro Moromizato, Rafaela Mego, Hernando Rafael, José Rodriguez

Case Rep Clin Pract Rev 2004; 5(null):481-486 :: ID: 12356


Background: Since 1997 we known that the revascularization in the posterior hypothalamic nuclei can normalize neurogenic hypertension and likewise,experimental and clinical studies suggest that
type 2 diabetes mellitus (DM) is a disorder of the hypothalamus.Case Report: Case 1 was a 75-year-old woman with type 2 DM,vertigo,mild Alzheimer´s disease(AD), olfactory deficit and daytime sleepiness. During 10 years with diabetes,her blood glucose fluctuated between 110 and 240 mg %. Case 2 is a 82-year-old man with a 14-year history of type 2 DM,and lately,he presented motor deficit,bladder dysfunction,arterial hypertension,visual impairment and siallorrhea. His glycemias varied between 115 and 175 mg%. Both patientswere treated with oral hypoglycemic agents. An omental transplantation on the optic chiasma and the carotid bifurcation was performed on both cases.Results: Neurological improvement began since the first days after the operation; especially the mild AD disappeared and neurogenic hypertension was normalized and without antihypertensive medication. Moreover ,they had normal levels of circulating blood glucose and with scarce antidiabetic medication.Conclusions: These neurosurgical findings indicate that ischemic neurons in the anterior hypothalamic nuclei are responsibles at the onset of type 2 DM( mild state ).

Keywords: Cerebral atherosclerosis, Hypothalamic ischemia, Omental transplantation., type 2 diabetes

Add Comment 0 Comments


In Press

Case report  Portugal

Bartter Syndrome Presenting as Arginine-Vasopressin Resistance: A Report of 2 Cases

Am J Case Rep In Press; DOI: 10.12659/AJCR.942872  

Case report  China (mainland)

Extended Left Hemihapatectomy with Right Hepatic Artery Reconstruction for Primary Hepatic Neuroendocrine N...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943721  

Case report  Austria

Smoking-Associated Endotracheal Hair Growth: A Case Report on Tracheal Complications

Am J Case Rep In Press; DOI: 10.12659/AJCR.943909  

Case report  Japan

Virtual Reality-Guided Simulation for Percutaneous Coronary Intervention in a Patient with Anatomical Anoma...

Am J Case Rep In Press; DOI: 10.12659/AJCR.944485  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA 38,124

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133


10 Jan 2022 : Case report  Germany 31,073

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia 17,693

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA 17,607

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923