Background: Effort related axillary-subclavian vein thrombosis or so called ‘Paget-Schroetter’s’ syndrome is a very rare form of deep vein thrombosis of the upper extremity. Case Report: Herein, three cases of Paget-Schrotter’s syndrome treated surgically were presented. All patients were young males with primary or effort thrombosis, whose vocation or avocation was associated with considerable muscular activity of their upper arms. The first case was an early case, who was treated with thrombectomy alone. The other cases were referred late 27, 32 days respectively. The second patient was treated with thrombectomy, vein patch plasty, partial claviclectomy and temporary arterio-venous (A-V) fistula. The third patient was treated with thrombectomy, endovenectomy, vein patch plasty, and temporary A-V fistula. Both fistula were ligated 4 weeks after the operation. Now, all patients are under periodic control, asymptomatic 16.9 and 5 years respectively.Conclusions: The gold standard for the success of the treatment is the early attendance, early diagnosis and appropriate treatment modality. Thrombolytic therapy, in appropriate cases must be the treatment of choice followed by surgical correction. But in chronic cases or whom attended late or did not respond to fibrinolytic therapy, achievement of best results and the treatment modality is yet to be defined.

Keywords: vein thrombosis, Paget-Schroetter’s syndrome, surgical treatment