Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 September 2003

Association of germ cell tumor and Langerhans histiocytosis in a 2-year old child

Małgorzata Szumera, Stefan Popadiuk, Anna Borkowska, Maria Korzon

Case Rep Clin Pract Rev 2003; 4(2):107-110 :: ID: 429045

Abstract

Background: Coincidence of various neoplasias in the same patients, as well as a hereditary predisposition to development of malignant neoplasms, arouses the interest of both geneticists and oncologists. Case Report: The paper presents a case of a 2-year-old girl, in whom two foci of Langerhans cell histiocytosis in the left parietal bone and right humerus were diagnosed 5 months after completion of chemotherapy with etoposide, ifosfamide and cisplatin combined with surgical resection of a malignant germ cell tumor of the sacrococcygeal region. Both histiocytosis foci were removed surgically. No relapses of either disease have been observed within 24 months after the completion of treatment. Laboratory tests reveal persistent increase of alkaline phosphatase level. Conclusions: A rare case of coincident two independent neoplastic processes – malignant germ cell tumor and Langerhans cell histiocytosis in a child is presented. Despite good treatment results obtained for both diseases, the follow-up period has been short and the child requires further clinical observation.

Keywords: germ cell tumor, langerhans cell histiocytosis, Association

Add Comment 0 Comments

81

In Press

Case report  Kosovo

A 74-Year-Old Man with Severe Comorbidities and Successful Abdominal Aortic Aneurysm Repair with Thoracic S...

Am J Case Rep In Press; DOI: 10.12659/AJCR.943702  

0:00

Case report  Vietnam

Fibrous Dysplasia of the Parietal Bone with Focal Motor Seizures: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.943718  

0:00

Case report  Saudi Arabia

Regenerative Endodontic Procedure on an Immature Necrotic Molar: A Case Report with a 5-Year Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.944179  

Case report  Italy

Minimally Invasive Surgical Management of Chronic Cough-Induced Rib Fracture Non-Union: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.943222  

Most Viewed Current Articles

07 Mar 2024 : Case report  USA 38,465

Neurocysticercosis Presenting as Migraine in the United States

DOI :10.12659/AJCR.943133

Am J Case Rep 2024; 25:e943133

0:00

10 Jan 2022 : Case report  Germany 31,136

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

19 Jul 2022 : Case report  Saudi Arabia 17,751

Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19

DOI :10.12659/AJCR.936128

Am J Case Rep 2022; 23:e936128

23 Feb 2022 : Case report  USA 17,750

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923