Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 September 2003

Association of germ cell tumor and Langerhans histiocytosis in a 2-year old child

Małgorzata Szumera, Stefan Popadiuk, Anna Borkowska, Maria Korzon

Case Rep Clin Pract Rev 2003; 4(2):107-110 :: ID: 429045

Abstract

Background: Coincidence of various neoplasias in the same patients, as well as a hereditary predisposition to development of malignant neoplasms, arouses the interest of both geneticists and oncologists. Case Report: The paper presents a case of a 2-year-old girl, in whom two foci of Langerhans cell histiocytosis in the left parietal bone and right humerus were diagnosed 5 months after completion of chemotherapy with etoposide, ifosfamide and cisplatin combined with surgical resection of a malignant germ cell tumor of the sacrococcygeal region. Both histiocytosis foci were removed surgically. No relapses of either disease have been observed within 24 months after the completion of treatment. Laboratory tests reveal persistent increase of alkaline phosphatase level. Conclusions: A rare case of coincident two independent neoplastic processes – malignant germ cell tumor and Langerhans cell histiocytosis in a child is presented. Despite good treatment results obtained for both diseases, the follow-up period has been short and the child requires further clinical observation.

Keywords: germ cell tumor, langerhans cell histiocytosis, Association

Add Comment 0 Comments

In Press

21 Sep 2023 : Case report  Cyprus

Successful Outpatient Treatment of Severe Diabetic-Foot Myositis and Osteomyelitis Caused by Extensively Dr...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941337  

21 Sep 2023 : Case report  Brazil

Fulminant Lymphocytic Myocarditis Successfully Managed with Intra-Aortic Balloon Pump and Extracorporeal Me...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941422  

21 Sep 2023 : Case report  Spain

Emphysematous Cystitis: A Rare Urologic Emergency

Am J Case Rep In Press; DOI: 10.12659/AJCR.941599  

21 Sep 2023 : Case report  Saudi Arabia

Use of a 2-Piece Small Diameter Implant in the Esthetic Zone in a Site of Chronic Residual Periapical Lesio...

Am J Case Rep In Press; DOI: 10.12659/AJCR.941877  

Most Viewed Current Articles

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923