Background: Primary cardiac tumors are infrequent, 0.0001–0.5% in autopsy series, but myxomas are the most common type of all such lesions. The incidence of right atrial myxomas (RAM) are much less common and range from 8.6% to 20% and are usually attached to the interatrial septum. Case Report: Here we report the case of a 58-years old woman who was operated twelve years ago for Right Atrial Myxoma in another medical center, experiencing recurrence with angina pectoris, palpitations, dyspnea and edema at lower extremities. The recurrens was identified by two-dimensional transthoracic echocardiography and was retreated surgically. Occuring on the inferior vena cava (IVC) and floating into the right atrium, the tumor was succesfully extirpated by cardiopulmonary bypass and total circulatory arrest. Conclusions: RAM originating from IVC may have a higher risk for recurrence as extirpation is not so controllable and exposure is somewhat more difficult to asses. Routine femoral cannulation will be the perfect choice for these patients. Inspection of four cardiac chambers with TEE is also required.

Keywords: right atrial myxoma, inferior vena caval origin, Recurrence