01 February 2006
Difficulties in the diagnosis of primary bilateral adrenal lymphomaUrszula Ambroziak, Bogusław Skórka, Maciej Otto, Ewa Bar-Andziak
Case Rep Clin Pract Rev 2006; 7:6-9 :: ID: 445548
Background: Primary adrenal lymphoma is a very rare condition. It usually occurs as a bilateral adrenal
mass. Patients usually do not have disease elsewhere what makes the diagnosis more difficult. The symptoms of disease are variable and depend on the presence of adrenal insufficiency, tumor size or lymphoma.
Case Report: We report a case of a 66-year-old woman who was evaluated due to anorexia and epigastric pain.
She was admitted to the Department of Endocrinology due to an incidental discovery of a large, bilateral adrenal mass. There was no history of weight loss, fever or night sweating. Physical examination revealed pale skin, orthostatic hypotension, splenomegaly without hepatomegaly and no abnormalities in the chest, head and neck. No peripheral lymph nodes were palpable. Results of dynamic hormonal tests confirmed the clinical diagnosis of adrenal insufficiency. During the observation tumors enlarged markedly. Adrenal hemorrhage or lymphoma was initially suspected. The result of a percutaneous needle biopsy of the right adrenal gland was inconclusive and no infiltration of lymphoma in the bone marrow led to the decision of an
adrenalectomy. The histopathological result was a diffuse large B cell lymphoma. Systemic
chemotherapy was initiated with CHOP regimen.
Conclusions: In the presence of bilateral rapidly growing adrenal mass, adrenal insufficiency, splenomegaly and no peripheral lymphadenopathy the diagnosis of primary adrenal non Hodgkin lymphoma
has to be taken into account.
Keywords: adrenals, adrenal insufficiency
21 March 2023 : Case reportKidney Transplantation from a Deceased Donor with COVID-19 Ad26.COV2-S Vaccine-Induced Thrombotic Thrombocy...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938730
21 March 2023 : Case reportClassical Presentation of Disseminated Blastomycosis in a 44-Year-Old Healthy Man 3 Months After Diagnosis ...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938659
22 February 2023 : Case reportA 30-Year-Old Woman with an 8-Week History of Anxiety, Depression, Insomnia, and Mild Cognitive Impairment ...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938732
22 February 2023 : Case reportMultidrug-Resistant Kocuria rosea and Methicillin-Resistant Staphylococcus aureus Co-Infection in a Nigeria...
Am J Case Rep In Press; DOI: 10.12659/AJCR.938761
22 Mar 2023 : Case reportLaparoscopic Cholecystectomy in a Patient with Situs Inversus Totalis and a Double Superior Vena Cava
Am J Case Rep In Press; DOI: 10.12659/AJCR.938774
22 Mar 2023 : Case reportRare Case of Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome with Monoclonal Gammo...
Am J Case Rep In Press; DOI: 10.12659/AJCR.939650
22 Mar 2023 : Case reportOral and Intranasal Ketamine Use in Treatment-Resistant Catatonia: A Clinical Case Report
Am J Case Rep In Press; DOI: 10.12659/AJCR.939530
22 Mar 2023 : Case reportAn Easily Missed But Life-Threatening Diagnosis: A Case Report of Gorlin Syndrome
Am J Case Rep In Press; DOI: 10.12659/AJCR.939117
Most Viewed Current Articles
13 Jul 2022 : Case reportWhistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound
Am J Case Rep 2022; 23:e936441
06 Dec 2021 : Case reportLipedema Can Be Treated Non-Surgically: A Report of 5 Cases
Am J Case Rep 2021; 22:e934406
23 Feb 2022 : Case reportPenile Necrosis Associated with Local Intravenous Injection of Cocaine
Am J Case Rep 2022; 23:e935250
07 Dec 2021 : Case reportEdwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...
Am J Case Rep 2021; 22:e934347