Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

01 February 2006

Integrin and Interleukin-1 Receptor Type I Expression in Pancreatic Tissue from a Patient with Chronic Pancreatitis Complicated with Pancreas Divisum: Report of a Case

Hirozumi Sawai, Hitoshi Funahashi, Yuji Okada, Yoichi Matsuo, Hiroki Takahashi, Hiromitsu Takeyama, Tadao Manabe

Case Rep Clin Pract Rev 2006; 7:44-47 :: ID: 446795

Abstract

Background: Any link between chronic pancreatitis and pancreatic cancer could reflect the malignant potential of a chronic inflammatory process. In this case report, we investigated the occurrence of a possible malignancy within the chronic pancreatitis tissue and present here a clinicopathological and
immunohistochemical features of a case of chronic pancreatitis with pancreas divisum.
Case Report: A 39-year-old Japanese man was admitted to our hospital, presenting with severe abdominal and
back pain due to chronic pancreatitis. Endoscopic retrograde pancreatography demonstrated the pancreas divisum, dilatation of the main pancreatic duct, and a cystic lesion in the accessory pancreatic duct of Santorini. Computed tomography demonstrated pancreatolithiasis in the whole pancreas. Under diagnosis of chronic pancreatitis with pancreas divisum, laparotomy was performed. Then a pylorus-preserving pancreaticoduodenectomy and side-to-side
pancreatojejunostomy were performed on suspicion of malignant disease in the pancreatic head. Immunohistochemical examination revealed the absence of p53 protein and presence of α[sub]6[/sub] integrin subunit and interleukin-1 receptor type I.
Conclusions: Our results indicated the possibility of malignancy in conjunction with chronic pancreatitis and pancreas divisum in this patient.

Keywords: chronic pancreatitis, Integrins, Pancreas divisum

0 Comments

SARS-CoV-2/COVID-19

21 March 2023 : Case report  Croatia

Kidney Transplantation from a Deceased Donor with COVID-19 Ad26.COV2-S Vaccine-Induced Thrombotic Thrombocy...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938730  

21 March 2023 : Case report  USA

Classical Presentation of Disseminated Blastomycosis in a 44-Year-Old Healthy Man 3 Months After Diagnosis ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938659  

22 February 2023 : Case report  Taiwan

A 30-Year-Old Woman with an 8-Week History of Anxiety, Depression, Insomnia, and Mild Cognitive Impairment ...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938732  

22 February 2023 : Case report  Nigeria

Multidrug-Resistant Kocuria rosea and Methicillin-Resistant Staphylococcus aureus Co-Infection in a Nigeria...

Am J Case Rep In Press; DOI: 10.12659/AJCR.938761  

In Press

22 Mar 2023 : Case report  Jordan

Laparoscopic Cholecystectomy in a Patient with Situs Inversus Totalis and a Double Superior Vena Cava

Am J Case Rep In Press; DOI: 10.12659/AJCR.938774  

22 Mar 2023 : Case report  USA

Rare Case of Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome with Monoclonal Gammo...

Am J Case Rep In Press; DOI: 10.12659/AJCR.939650  

22 Mar 2023 : Case report  USA

Oral and Intranasal Ketamine Use in Treatment-Resistant Catatonia: A Clinical Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.939530  

22 Mar 2023 : Case report  Greece

An Easily Missed But Life-Threatening Diagnosis: A Case Report of Gorlin Syndrome

Am J Case Rep In Press; DOI: 10.12659/AJCR.939117  

Most Viewed Current Articles

13 Jul 2022 : Case report  USA

Whistling Scrotum: An Unusual Presentation of Pneumomediastinum in the Setting of an Open Scrotal Wound

DOI :10.12659/AJCR.936441

Am J Case Rep 2022; 23:e936441

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

23 Feb 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

DOI :10.12659/AJCR.935250

Am J Case Rep 2022; 23:e935250

07 Dec 2021 : Case report  USA

Edwardsiella tarda: A Classic Presentation of a Rare Fatal Infection, with Possible New Background Risk Fac...

DOI :10.12659/AJCR.934347

Am J Case Rep 2021; 22:e934347

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923